Results 61 to 70 of about 1,965,480 (316)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Research Naval Postgraduate School, v.5, no. 1, April 1995

open access: yes, 1995
NPS Research is published by the Research and Sponsored Programs, Office of the Vice President and Dean of Research, in accordance with NAVSOP-35.

core  

Research Naval Postgraduate School, v.13, no.1, February 2003 [PDF]

open access: yes, 2003
NPS Research is published by the Research and Sponsored Programs, Office of the Vice President and Dean of Research, in accordance with NAVSOP-35. Views and opinions expressed are not necessarily those of the Department of the Navy.Approved for public ...

core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Review Essay: Reporting Large-Scale Qualitative Research: The Ergography

open access: yesForum: Qualitative Social Research, 2008
As social science research programmes tend to increase in scale, reporting their results in a coherent manner is growing more difficult. Andrew WEBSTER's edited volume presents a wealth of social science research and is a pleasant read for many reasons ...
Bart Penders, Annemiek Nelis
doaj  

Endothelial Pim3 kinase protects the vascular barrier during lung metastasis

open access: yesNature Communications
Endothelial cells (ECs) form a tissue-specific barrier for disseminating cancer cells in distant organs. However, the molecular regulation of the ECs in the metastatic niche remains unclear.
Niina M. Santio   +9 more
doaj   +1 more source

Loss of mtDNA activates astrocytes and leads to spongiotic encephalopathy

open access: yesNature Communications, 2018
Astrocytes in the brain are metabolically dynamic. Here, Ignatenko, Chilov and colleagues delete mitochondrial DNA (mtDNA) in a cell type specific manner, and show that inactivation of mtDNA helicase Twinkle in astrocytes leads to spongiotic ...
Olesia Ignatenko   +9 more
doaj   +1 more source

Research Naval Postgraduate School, v.4, no. 2, December 1994

open access: yes, 1994
NPS Research is published by the Research and Sponsored Programs, Office of the Vice President and Dean of Research, in accordance with NAVSOP-35.

core  

Research Naval Postgraduate School, v. 4, no. 13, September 2012 [PDF]

open access: yes, 2012
NPS Research is published by the Research and Sponsored Programs, Office of the Vice President and Dean of Research, in accordance with NAVSOP-35. Views and opinions expressed are not necessarily those of the Department of the Navy.Approved for public ...

core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy