Results 151 to 160 of about 901,210 (313)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Open Access: the future of scholarly communication [PDF]

open access: yes, 2005
Advances in scholarship rely on the effective communication of research results. Discoveries need to be widely disseminated so that other researchers can build on them and contribute to an ever-expanding body of knowledge.
Prosser, David C.
core  

Analysis of Opportunity in Novel Medical Research Ideas using AI Systems

open access: yesApplied Medical Informatics
This project and paper present a system for automated analysis of medical research articles, designed to support literature triage and the identification of potentially high-opportunity research topics.
Raul-Mihai RĂDULESCU   +5 more
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Proceedings of the sixteenth ERME topic conference on language and social interaction in heterogeneous mathematics classrooms [PDF]

open access: yes
Design-based research frequently has a two-pronged aim namely, focusing on both a specific mathematical topic and a wider instructional issue (Prediger et al., 2015).
Sixteenth ERME Topic Conference on Language and Social Interaction in Heterogeneous Mathematics Classrooms   +1 more
core  

An architecture for organisational decision support [PDF]

open access: yes, 2007
The Decision Support (DS) topic of the Network Enabled Capability for Through Life Systems Engineering (NECTISE) project aims to provide organisational through-life decision support for the products and services that BAE Systems deliver.
Whitfield, R.I.   +4 more
core  

A Model of Decision Support System for Research Topic Selection and Plagiarism Prevention

open access: yesThe International Journal of Engineering and Science, 2017
Dr. Hardik B. Pandit, Dr. Dipti B. Shah
openaire   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Naval Research Program Sharpening the Spear Naval Postgraduate School [PDF]

open access: yes, 2018
The Naval Postgraduate School (NPS) Naval Research Program (NRP) is funded by the Chief of Naval Operations and supports research projects for the Navy and Marine Corps.

core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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