Results 61 to 70 of about 85,046,577 (291)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Pseudodementia, pseudo‐pseudodementia, and pseudodepression

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2020
Dementia has a wide range of reversible causes. Well known among these is depression, though other psychiatric disorders can also impair cognition and give the appearance of neurodegenerative disease.
Henry Brodaty, Michael H. Connors
doaj   +1 more source

Exploring Abnormal Behavior Patterns of Online Users With Emotional Eating Behavior: Topic Modeling Study

Journal of Medical Internet Research, 2020
BackgroundEmotional eating (EE) is one of the most significant symptoms of various eating disorders. It has been difficult to collect a large amount of behavioral data on EE; therefore, only partial studies of this symptom have been conducted. To provide
Hwang, Youjin, Kim, Hyung Jun, Choi, Hyung Jin, Lee, Joonhwan   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A bibliometric analysis of research on trade remedies [PDF]

Problems and Perspectives in Management
This study aims to explore the research landscape and identify the main research directions related to the topic of trade remedies. The research data were collected by accessing the Scopus database with 289 documents and the WoS database with 75 ...
Long Tran Viet, Hai Phan Thanh
doaj   +1 more source

Research on the topic discovery and hotspot evolution of the LIS field from the perspective of papers supported by the National Foundation

Journal of Education, Humanities and Social Sciences, 2022
Exploring the fine-grained characteristics of the results of papers funded by national funds is helpful to help researchers more accurately grasp the research hotspots and frontier trends of the discipline to identify the frontier topics of scientific research.
openaire   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Functional similarities between bimanual coordination and topic/comment structure [PDF]

, 2007
Human manual action exhibits a differential use of a non-dominant (typically, left) and a dominant (typically, right) hand. Human communication exhibits a pervasive structuring of utterances into topic and comment.
Manfred Krifka, Krifka, Manfred
core   +1 more source

Scaleup tests and supporting research for the development of duct injection technology. Topical report No. 1, Literature review [PDF]

, 1989
Gilbert Commonwealth, Southern Research Institute and the American Electric Power Service Corporation have embarked on a program to convert DOE`s Duct Injection Test Facility located at the Muskingum River Power Plant of Ohio Power Company to test alternate duct injection technologies.
Gooch, J. P., Dismukes, E. B., Dahlin, R. S., Faulkner, M. G., Klett, M. G., Buchanan, T. L., Hunt, J. E.   +6 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source