Results 71 to 80 of about 1,861,022 (256)
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Injury prevention strategies at the FIFA 2014 World Cup: perceptions and practices of the physicians from the 32 participating national teams [PDF]
, 2015 Purpose The available scientific research regarding injury prevention practices in international football is sparse. The purpose of this study was to quantify current practice with regard to (1) injury prevention of top-level footballers competing in an ...
Alan McCall +41 more
core +3 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Design Researchers Leading Interdisciplinary Teams
Diseña, 2018 This special issue of Diseña seeks to articulate and describe interdisciplinary examples of design-led research, posing questions such as: in what ways are such projects addressing matters of concern, what are the defining traits of such projects, and ...
Stan Ruecker
doaj +7 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
The Pythagorean Won-Loss Formula and Hockey: A Statistical Justification for Using the Classic Baseball Formula as an Evaluative Tool in Hockey [PDF]
, 2013 Originally devised for baseball, the Pythagorean Won-Loss formula estimates the percentage of games a team should have won at a particular point in a season. For decades, this formula had no mathematical justification.
Dayaratna, Kevin D., Miller, Steven J.
core
Building the Infrastructure: The Effects of Role Identification Behaviors on Team Cognition Development and Performance [PDF]
, 2010 The primary purpose of this study was to extend theory and research regarding the emergence of mental models and transactive memory in teams. Utilizing Kozlowski et al.’s (1999) model of team compilation, we examine the effect of role identification ...
Bell, Bradford S +2 more
core +3 more sources
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Two coaches operating as a ‘learning pair’ [PDF]
International Journal of Evidence Based Coaching and Mentoring, 2013 Whilst an established aid to personal development, coaching is still in its early stages of maturity. So too, outside of the field of education, is the concept of learning teams. This paper concerns coach development via two complementary coaches working
Michael Smith, Rebekah Gilbert
doaj