Results 181 to 190 of about 52,779,818 (301)

Biobanking in Ireland: Moving Forward. Irish Health Research Forum Recommendations and Event Report [PDF]

open access: yes
This report presents the proceedings of the Irish Health Research Forum on November 16th 2023, focusing on progressing biobanking in Ireland, and makes key recommendations for moving biobanking forward.Roche Products ...
Health Research Charities Ireland
core  

Worldwide productivity and research trend of publications concerning tumor immune microenvironment (TIME): a bibliometric study. [PDF]

open access: yesEur J Med Res, 2023
Liu YG   +9 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Global research trend and foci of oral lichen planus: A bibliometric analysis from 2014 to 2023. [PDF]

open access: yesMedicine (Baltimore)
Bu X   +6 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Microalgal-bacterial interactions: Research trend and updated review. [PDF]

open access: yesHeliyon
Iqhrammullah M   +5 more
europepmc   +1 more source

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