Results 121 to 130 of about 5,617,166 (283)
Frontiers in NeuroscienceSpatial group independent component analysis (sgr-ICA) is widely used in resting-state fMRI to identify intrinsic connectivity networks (ICNs). While lower-order decompositions reveal large-scale networks, higher-order models provide finer granularity ...
Shiva Mirzaeian +15 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
New trends in combustion research for gas turbine engines [PDF]
Research on combustion is being conducted to provide improved analytical models of the complex flow and chemical reaction processes which occur in the combustor of gas turbine engines, in order to enable engine manufacturers to reduce the development ...
Mularz, E. J.
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Input-Output in Europe: Trends in Research and Application [PDF]
Indubitably born in the USA, input-output analysis has an important European history, from its very beginnings in the Soviet Union to the postwar huge development of I/O techniques in West and North Europe.
Akhabbar, Amanar +3 more
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Combining fast and slow fMRI sampling rates can enhance predictive power in resting-state data
NeuroImageData collection technology in functional magnetic resonance imaging (fMRI) is rapidly developing, leading to continuous growth of spatio-temporal resolution.
Joanne Wardell +9 more
doaj +1 more source
An Econometric Analysis of Trends in Research Joint Venture Activity. [PDF]
Edith Penrose was one of the first scholars to point out that firms may need to rely on research joint ventures (RJVs) to acquire access to resources that can help them achieve and sustain a competitive advantage.
Albert N. Link +2 more
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source