Results 131 to 140 of about 848,850 (261)

Restoring thoracic stability with rigid titanium rib reconstruction after radical forequarter and upper chest wall resection for T4 chondrosarcoma. [PDF]

J Surg Case Rep
Rifa'i AD, Raz HF, Duha MH, Sihombing NMI, Pahlevi MFP.   +4 more
europepmc   +1 more source

UCtracker: A Deep Learning–Based DNA Methylation Model for Noninvasive Diagnosis and Recurrence Surveillance of Urothelial Carcinoma in a Prospective Study

Advanced Science, EarlyView.
We developed UCtracker, a urine DNA methylation–based deep learning model, for noninvasive diagnosis and postoperative surveillance of urothelial carcinoma. UCtracker demonstrates high diagnostic accuracy, robustness at ultralow sequencing depth, early recurrence detection, and dynamic risk‐stratified monitoring of molecular residual disease ...
Shengwei Xiong, Gaojie Li, Yucai Wu, Yuan Liang, Heng Guo, Yu Zhang, Gengyan Xiong, Long Tian, Xin Zhang, Ye Tian, Zhengguo Ji, Bin Guo, Yue Shi, Jian Fan, Zhihua Li, Yanqing Gong, Shiming He, Xuesong Li, Weimin Ci, Liqun Zhou   +19 more
wiley   +1 more source

Posterior fossa ependymoma: a comprehensive review of molecular classification, management guidelines, and clinical outcomes (Part I of ependymomas across compartments). [PDF]

J Neurooncol
Koutsouras GW, Rivera F, Price AM, Tsang DS, Esbenshade A, Ramaswamy V, Dirks PB, Dewan MC.   +7 more
europepmc   +1 more source

O‐GlcNAcylation Regulation of SNAP29‐Dependent Autophagy Activation Dictates Chemoresistance in Gastric Cancer

Advanced Science, EarlyView.
Model illustrating the proposed mechanism by which chemotherapy‐induced downregulation of OGT disrupts SNAP29 O‐GlcNAcylation, promoting STX17‐SNAP29‐VAMP8 SNARE complex assembly and protective autophagy, leading to chemoresistance, which in turn establishes a feedforward loop to perpetuate drug tolerance.
Liang Tang, Shaoji Zhao, Ziling Shao, Tao Luo, Baifu Peng, Yifan Liu, Jinning Ye, Jianjun Peng, Kaiyu Sun, Jianbo Xu   +9 more
wiley   +1 more source

Upfront surgery vs. neoadjuvant therapy in pancreatic cancer with venous involvement: a multicenter retrospective analysis. [PDF]

Langenbecks Arch Surg
Halimi A, Zwart ES, Yilmaz BS, Kurlinkus B, Ahola R, Del Chiaro M, Sparrelid E, Rangelova E, Maggino L, Malleo G, Lionetto G, Salvia R, Roberts KJ, Giovinazzo F, Falconi M, Crippa S, Belfiori G, Kazemier G, Maisonneuve P, Laukkarinen J, Ceyhan GO.   +20 more
europepmc   +1 more source

Agent‐Based Simulations of Lung Tumor Evolution Suggest That Ongoing Cell Competition Drives Realistic Clonal Expansions

Advanced Science, EarlyView.
Computational simulations of tumor evolution are increasingly used to infer the rules underlying cancer growth, with the goal of one day recommending tailored treatments. Here we show that the properties of lung cancer sequencing data are best replicated by a model which assumes that cells compete both to proliferate and survive. ABSTRACT Computational
Helena Coggan, James R. M. Black, Carlos Martínez‐Ruiz, Kristiana Grigoriadis, Jasmin Fisher, Nicholas McGranahan   +5 more
wiley   +1 more source

Major liver necrosis after blunt trauma. [PDF]

Trauma Surg Acute Care Open
Braschi C, Ley EJ, Cross A, Dougherty-Welch S, Matsushima K.   +4 more
europepmc   +1 more source

Nanovesicles With Mechanically Induced Adjuvanticity for Robust Melanoma Vaccination Toward Tumor‐Associated Macrophages

Advanced Science, EarlyView.
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley   +1 more source

Pathological Complete Response after Conversion Surgery for Distal Cholangiocarcinoma with High Tumor Mutational Burden and Para-Aortic Lymph Node Metastasis: A Case Report. [PDF]

Surg Case Rep
Hatano K, Okamura Y, Nakao K, Tanke G, Yamamoto G, Uryuhara K, Narita M, Hara S, Kaihara S.   +8 more
europepmc   +1 more source

Cricotracheal Resection [PDF]

Ear, Nose & Throat Journal, 2015
Amanda, Hu, James, McCaffrey, Al, Hillel
openaire   +2 more sources