Results 111 to 120 of about 1,106,310 (293)

Simultaneous reconstruction of the oral commissure, lip and buccal mucosa with microvascular transfer of combined first-second toe web and dorsalis pedis flap [PDF]

, 2016
The reconstruction of oral commissure, lip and mucosa defects following tumour resection is a challenging task to the reconstructive surgeon owing to the increasing aesthetic and functional demands.
Chen, Hung-Chi, Ciudad, Pedro, Maruccia, Michele, Sapountzis, Stamatis   +3 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Pericardial cyst due to tuberculosis in an adolescent

Annals of Cardiac Anaesthesia, 2008
Patient with a mediastinal mass may be diagnosed incidentally or following evaluation for the symptoms due to compressive effects on the adjoining structures. Pericardial cysts account to 6% of mediastinal masses.
Venkatesh B, Girotra Samir, Iyer Krishna, Chakrabarti Manisha, Khurana Poonam, Sen Ashok   +5 more
doaj  

Outcomes after pneumonectomy versus limited lung resection in adults with traumatic lung injury. [PDF]

, 2020
Pneumonectomy after traumatic lung injury (TLI) is associated with shock, increased pulmonary vascular resistance, and eventual right ventricular failure. Historically, trauma pneumonectomy (TP) mortality rates ranged between 53 and 100%.
Doben, Andrew R, Dolich, Matthew, Grigorian, Areg, Gross, Ronald, Homo, Richelle L, Kuza, Catherine M, Lekawa, Michael, Nahmias, Jeffry   +7 more
core  

DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2 [PDF]

, 2010
The repair of DNA double-strand breaks (DSBs) by homologous recombination requires processing of broken ends. For repair to start, the DSB must first be resected to generate a 3′-single-stranded DNA (ssDNA) overhang, which becomes a substrate for the DNA
AV Nimonkar, B Llorente, BO Krogh, C Zierhut, DG Anderson, E Alani, E Hartsuiker, Elda Cannavo, EP Mimitou, FG Harmon, HI Kao, I Chiolo, J LeBowitz, JA Cobb, JA Solinger, JR Mullen, Judith L. Campbell, KH Bae, L Wu, M Chang, ME Budd, ME Budd, ME Budd, MJ Neale, MS Dillingham, N Handa, P Cejka, P Szankasi, Petr Cejka, Piotr Polaczek, S Gangloff, S Gravel, SH Bae, SH Bae, Stephen C. Kowalczykowski, Subhash Pokharel, T Masuda-Sasa, Taro Masuda-Sasa, TH Stracker, X Li, Z Zhu   +40 more
core   +4 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Experience in hepatic resection for metastatic colorectal cancer: Analysis of clinical and pathologic risk factors [PDF]

, 1994
Background. The selection of patients for resective therapy of hepatic colorectal metastases remains controversial. A number of clinical and pathologic prognostic risk factors have been variably reported to influence survival. Methods.
Doerr, RJ, Gayowski, TJ, Irish, W, Iwatsuki, S, Madariaga, JR, Otta, D, Selby, R, Starzl, TE, Todo, S, Williams, JW   +9 more
core  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Moving Mountains—The BRCA1 Promotion of DNA Resection

Frontiers in Molecular Biosciences, 2019
DNA double-strand breaks (DSBs) occur in our cells in the context of chromatin. This type of lesion is toxic, entirely preventing genome continuity and causing cell death or terminal arrest.
Ruth M. Densham, Joanna R. Morris
doaj   +1 more source