Results 61 to 70 of about 1,222,531 (345)

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Primary tracheo‐bronchial adenoid cystic carcinoma: A surgical series with literature review

Respirology Case Reports
Tracheo‐bronchial adenoid cystic carcinoma (TBACC) is a rare disease. Its treatment is mainly surgical. We herein describe the clinical and para‐clinical varieties of TBACC as well as their surgical treatment and prognosis.
Kaouther Ben Amara, Imen Bouassida, Rahma Ayadi, Mariem Affes, Amina Abdelkbir, Mahdi Abdennadher, Salma Ben Othmen, Ayda Ayadi‐Kaddour, Hazem Zribi, Adel Marghli   +9 more
doaj   +1 more source

Real-world treatment patterns and outcomes in patients with early-stage HCC in the US treated with resection or ablation

Hepatic Oncology
Aim Real-world outcomes in early-stage hepatocellular carcinoma (eHCC) are not well characterized. We aimed to evaluate treatment patterns and long-term outcomes in patients with eHCC treated with resection or ablation in the United States.Materials and ...
Neehar D. Parikh, Ravi Patel, Jenny Hu, Heide A. Stirnadel-Farrant, Nehemiah Kebede, Cindy Wang, Kirema Garcia-Reyes   +6 more
doaj   +1 more source

The Art of Intraoperative Glioma Identification

Frontiers in Oncology, 2015
A major dilemma in brain tumor surgery is the identification of tumor boundaries to maximize tumor excision and minimize postoperative neurological damage.
Zoe Z Zhang, Lisa B.E. Shields, David eSun, Yi Ping eZhang, Matthew A Hunt, Christopher Brian Shields, Christopher Brian Shields   +6 more
doaj   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Nomograms to predict long‐term survival for patients with gallbladder carcinoma after resection

Cancer Reports
Background Surgical resection remains the primary treatment option for gallbladder carcinoma (GBC). However, there is a pressing demand for prognostic tools that can refine patients' treatment choices and tailor personalized therapies accordingly.
Shilei Bai, Pinghua Yang, Jiliang Qiu, Jie Wang, Liu Liu, Chunyan Wang, Huifeng Wang, Zhijian Wen, Baohua Zhang   +8 more
doaj   +1 more source

Hepatic Angiomyolipoma: A Case Report and Review of the Literature

Lietuvos Chirurgija, 2023
Background. Hepatic angiomyolipomas are uncommon non-cancerous mesenchymal tumors that belong to the perivascular epithelioid cell tumour group. Smooth muscle cells, fat cells and blood vessels can be observed in these types of neoplasm.
Jekaterina Strelčenko, Justas Kuliavas, Eugenijus Stratilatovas, Audrius Dulskas   +3 more
doaj   +1 more source

RESECTION OF THE CECUM. [PDF]

JAMA: The Journal of the American Medical Association, 1901
In January, 1900, Miss S. presented herself to me complaining of severe and almost constant pain in the right iliac region, and also of persistent constipation, which latter condition at times amounted to obturation. The previous history was negative, the patient having no memory of former illness, nor of intestinal or other disease.
openaire   +2 more sources

Laparoscopic resection of gastric GISTs. Where do we stand now? A single-centered experience [PDF]

, 2019
Introduction. Gastrointestinal stromal tumors (GISTs) represent a rare type of gastrointestinal neoplasms. Resection with negative margins has been established as a mainstay treatment, but laparoscopic resections are still open to debate.
Alecu, Lucian, Nitipir, Cornelia, Slavu, Iulian, Stanculeanu, Dana L, Tulin, Adrian   +4 more
core   +2 more sources

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source