Results 21 to 30 of about 165,970 (295)

Whole-Transcriptome Analysis of Yak and Cattle Heart Tissues Reveals Regulatory Pathways Associated With High-Altitude Adaptation

Frontiers in Genetics, 2021
BackgroundThe yak (Bos grunniens) is an important livestock species that can survive the extremely cold, harsh, and oxygen-poor conditions of the Qinghai-Tibetan Plateau and provide meat, milk, and transportation for the Tibetans living there.
Hui Wang, Hui Wang, Jincheng Zhong, Jincheng Zhong, Jikun Wang, Jikun Wang, Zhixin Chai, Zhixin Chai, Chengfu Zhang, Jinwei Xin, Jiabo Wang, Jiabo Wang, Xin Cai, Xin Cai, Zhijuan Wu, Zhijuan Wu, Qiumei Ji   +16 more
doaj   +1 more source

Status of Women in India and in Arunachal Pradesh: A Comparative study

Dera Natung Government College Research Journal, 2016
The right to equality between men and women is a fundamental right in Indian Constitution. Respect for the dignity of women has been made a fundamental duty of Indian citizens and all actions derogatory to such dignity are liable to be stuck down ...
Ram Krishna Mandal
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

A Smart Hybrid System for Parking Space Reservation in VANET [PDF]

Journal of Advances in Computer Engineering and Technology, 2017
Nowadays, developed and developing countries using smart systems to solve their transportation problems. Parking guidance intelligent systems for finding an available parking space, are considered one of the architectural requirements in transportation ...
Farhad Rad, hadi pazhokhzadeh, hamid parvin   +2 more
doaj  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Exploring the use of the RISK21 approach for Indigenous community-based human health risk assessments: two case studies

FACETS
Indigenous peoples in North America are disproportionately exposed to environmental contaminants and may face elevated health risks related to unique socio-cultural ties to the land. Conventional human health risk assessment (HHRA) methods do not account
Katherine Chong, Madisan Chavez, Ave Dersch, John Doyle, Margaret Eggers, JoRee LaFrance, Myra J Lefthand, Findlay MacDermid, Claire McAuley, Vanessa Simonds, Sara L Young, Niladri Basu   +11 more
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Tribally-led mobile outreach: improving access to harm reduction services in one rural reservation community

Frontiers in Public Health
American Indian and Alaska Native populations in the United States face significant disparities related to opioid use disorder and opioid-related mortality.
Allyson Kelley, Kellie Webb, Katherine Hirchak, Morgan Witzel, Kelsey Bajet, Sadie Posey   +5 more
doaj   +1 more source

Reliability assessment of cluster supercomputer configuration

Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2019
The study of reliability indicators was carried out on the example of a cluster supercomputer configuration of “SKIF-GEO” (further cluster) worked out within the framework of the scientific and technical program “SKIF-Nedra” (2015–2018, Program of the ...
L. I. Kulbak, O. P. Tchij, N. N. Paramonov, A. G. Rymarchuk, T. S. Martinovich   +4 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source