Results 161 to 170 of about 715,165 (308)
Operationalizing perioperative clearance reserve: a reserve-load interaction model for neurocognitive outcomes in older surgical patients. [PDF]
Front Med (Lausanne)La B, Bai Y, Qiu Y, Wang L.
europepmc +1 more source
, 1870 Surveyed by John Trutch and drawn by H.B. Launders, November 1870. [Not signed by Superintendent of Indian Affairs.] Tracing of a map showing several Reserves along the Fraser River including 21 - Ohamil Indian Reserve on left bank of Fraser River about
Surveyor General of British Columbia
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
, 1870 Surveyed by John Trutch and drawn by H.B. Launders, November 1870. [Not signed by Superintendent of Indian Affairs.] Map showing several Reserves along the Fraser River including 21 - Ohamil Indian Reserve on left bank of Fraser River about 10 miles ...
Surveyor General of British Columbia
core
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Coordinated optimization of reserve fund scale and emergency resource allocation for power utilities under multi-type large-scale blackout risks. [PDF]
PLoS OneGu Y, Zhang Z, Zhang L.
europepmc +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Association of <i>MTHFR</i> C677T and A1298C Polymorphisms with Ovarian Reserve in Infertile Women with Thyroid Autoimmunity. [PDF]
BiomedicinesSušanj Šepić T +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source