Results 181 to 190 of about 293,177 (261)

Land-Use Shapes Soil Fungal Communities and Functional Guilds in Tropical Forest Ecosystems. [PDF]

Plant Environ Interact
Olanipon D, Boeraeve M, Iyiola A, Wahab M, Jacquemyn H.   +4 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A protocol for validation of novel artificial intelligence-based framework for dyspnoea investigation with cardiopulmonary exercise testing. [PDF]

ERJ Open Res
Hijleh AA, Berton DC, James MD, Smyth RM, Vincent SG, Coyle M, Phillips D, Elbehairy AF, Domnik NJ, O'Donnell DE, Neder JA.   +10 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Habitat Quality, Conservation Gaps, and Environmental Suitability of Siberian Cranes (<i>Leucogeranus leucogeranus</i>) in the Erlongtao River Basin, Songnen Plain. [PDF]

Biology (Basel)
Wen Y, Jiang H, Zhu S, You J, Yue H, Teng H, He C.   +6 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Evolutionary game analysis of emergency medical supply production capacity reserves in nonprofit organizations: A theoretical perspective. [PDF]

PLoS One
Xiao H, Luo G, Wang Y, Shuang H, Li B.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Investigation of the suitable habitat for giant pandas and optimization of protected areas under the coupling of the maxent and marxan models: a case study of the Qionglai Mountains region. [PDF]

BMC Ecol Evol
Xie L, Liu J, Xu Y, Shi Y, Wang C, Chen H, Zhang Q, Wang Z, Li J.   +8 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source