Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
Growth dynamics and compensatory mechanisms in fish under fasting and refeeding regimes. [PDF]
Khormi MA.
europepmc +1 more source
Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley +1 more source
Analysis of different methods to calculate tertiary regulation reserves for renewable energy in Japan. [PDF]
Fonseca JGS, Hori T, Ogimoto K.
europepmc +1 more source
In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller +3 more
wiley +1 more source
Intergenerational Knowledge Exchange in Japanese Biosphere Reserves: Community Perceptions from Aya and Mount Hakusan. [PDF]
Mammadova A +5 more
europepmc +1 more source
Energy costs of Hannibal's alpine crossing. [PDF]
Berti E, Vollrath F.
europepmc +1 more source
The role of non-structural carbohydrates in tree physiology and forest management: a comprehensive review. [PDF]
Huang G +6 more
europepmc +1 more source
Regulatory landscapes of five mental health professions in Europe - a descriptive study based on the insights from the European Commission database. [PDF]
Kilkku N, Lewis C, Kearns T, Shannon M.
europepmc +1 more source
Trees just go "nuts": prioritizing carbon allocation to yield in almond trees. [PDF]
Veeravelli SS +11 more
europepmc +1 more source

