Results 31 to 40 of about 355,494 (269)

Petrographic image classification of complex carbonate rocks from the Brazilian pre-salt using convolutional neural networks

open access: yesScientific Reports
Machine learning (ML) algorithms have been widely applied across geosciences for tasks such as data conditioning, resolution enhancement, and image classification.
Mateus Basso   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Anisotropy and Energy Evolution Characteristics of Shales: A Case Study of the Longmaxi Formation in Southern Sichuan Basin, China

open access: yesGeofluids
To obtain the influence of anisotropy and energy evolution characteristics on wellbore stability, the acoustic and mechanical anisotropy characteristics of shales are studied through various experiments, including scanning electron microscopy, ultrasonic
Liu Xiangjun   +8 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The quantitative prediction of tectonic fractures of Longmaxi formation in Dingshan area, southeastern Sichuan Basin

open access: yesEarth Sciences Research Journal, 2019
Tectonic fractures are a significant factor for production of the Longmaxi formation in Dingshan area. The analyse of the distribution and development degree of tectonic fractures is the main research method in present-day.
Jiatong Xie   +4 more
doaj   +1 more source

Iteratively Coupled Flow and Geomechanics in Fractured Poroelastic Reservoirs: A Phase Field Fracture Model

open access: yesGeofluids, 2021
Fluid-solid coupling in fractured reservoirs plays a critical role for optimizing and managing in energy and geophysical engineering. Computational difficulties associated with sharp fracture models motivate phase field fracture modeling.
Jinzhou Zhao   +8 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Biological Stoichiometry Regulates Toxin Production in Microcystis aeruginosa (UTEX 2385)

open access: yesToxins, 2019
Harmful algal blooms (HABs) are increasing in magnitude, frequency, and duration globally. Even though a limited number of phytoplankton species can be toxic, they are becoming one of the greatest water quality threats to public health and ecosystems due
Nicole D. Wagner   +7 more
doaj   +1 more source

Fossil Diatoms Reveal Natural and Anthropogenic History of Jackson Lake (Wyoming, USA)

open access: yesEarth Science, Systems and Society, 2023
Jackson Lake supplies valuable cultural and provisioning ecosystem services to the Upper Snake River watershed in Wyoming and Idaho (western USA). Construction of Jackson Lake Dam in the early 20th century raised lake level by ∼12 m, generating an ...
John Dilworth   +4 more
doaj   +1 more source

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