Results 41 to 50 of about 355,494 (269)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Mechanical Properties of Different Lithological Rocks: A Case Study of the Coal Measure Strata in the Eastern Margin of Ordos Basin, China

open access: yesGeofluids, 2022
In this paper, the mechanical behaviors of different lithological rocks of coal measure strata from Shanxi Formation in the eastern margin of the Ordos Basin, China, were investigated through uniaxial compression tests, and the deformation ...
Xiong Jian   +5 more
doaj   +1 more source

HYDROCHEMICAL PARAMETERS AND BIOMETRIC DATA OF FISH SPECIES FROM THE BORORÉ, BILLINGS RESERVOIR, SÃO PAULO, BRAZIL

open access: yesBoletim do Instituto de Pesca, 2021
The artisanal fishing is an important activity in Billings Reservoir (São Paulo, Brazil) and there is a paucity of biometric data about the fish in this region.
Fabiana Harumi MIYASAKI   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Soil to Sheath: Nocardia Flexor Tenosynovitis in an Immunocompetent Pottery Artist

open access: yesJournal of Hand Surgery Global Online
Stenosing flexing tenosynovitis (trigger finger) is a chronic, noninfectious condition of the flexor tendon sheath, whereas infectious flexor tenosynovitis is an acute hand infection that requires urgent recognition and treatment.
James Anundson, MS, BS   +2 more
doaj   +1 more source

Antimicrobial use and resistance in Escherichia coli from healthy food-producing animals in Guadeloupe

open access: yesBMC Veterinary Research, 2021
Background Selection pressure exerted by use of antibiotics in both human and veterinary medicine is responsible for increasing antimicrobial resistance (AMR). The objectives of this study were to better understand antimicrobial use in pigs, beef cattle,
Gaëlle Gruel   +7 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Invasive freshwater jellyfish has become established in artificial impoundments of Anatolian Peninsula

open access: yesTurkish Journal of Bioscience and Collections, 2021
Objective: A freshwater jellyfish Craspedacusta sowerbii is frequently found in disturbed or artificial bodies of water, e.g. quarry ponds and gravel pits, reservoirs, aquaria and even wastewater treatment facilities, it can also thrive in natural lentic
Nurçin Killi   +8 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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