Results 41 to 50 of about 1,489,062 (321)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

The quantitative prediction of tectonic fractures of Longmaxi formation in Dingshan area, southeastern Sichuan Basin

Earth Sciences Research Journal, 2019
Tectonic fractures are a significant factor for production of the Longmaxi formation in Dingshan area. The analyse of the distribution and development degree of tectonic fractures is the main research method in present-day.
Jiatong Xie, Qirong Qin, Cunhui Fan, Dongfeng Hu, Hu Li   +4 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Anisotropy and Energy Evolution Characteristics of Shales: A Case Study of the Longmaxi Formation in Southern Sichuan Basin, China

Geofluids
To obtain the influence of anisotropy and energy evolution characteristics on wellbore stability, the acoustic and mechanical anisotropy characteristics of shales are studied through various experiments, including scanning electron microscopy, ultrasonic
Liu Xiangjun, Zhuang Dalin, Xiong Jian, Zhou Yishan, Liu Junjie, Deng Chong, Liang Lixi, Ding Yi, Jian Xuemei   +8 more
doaj   +1 more source

Switching from a protease inhibitor-based regimen to a dolutegravir-based regimen : a randomized clinical trial to determine the effect on peripheral blood and ileum biopsies from antiretroviral therapy-suppressed human immunodeficiency virus-infected individuals [PDF]

, 2018
Background: Optimization of combination antiretroviral therapy (cART) can impact the human immunodeficiency virus (HIV) reservoir. We evaluated the effect on the HIV reservoir in peripheral blood and ileum biopsies in patients switching from boosted ...
Blanco, Julià, Crespo, Manel, De Clercq, Laura, Gálvez, Cristina, Jimenez, Montse, Martinez-Picado, Javier, Moron-Lopez, Sara, Navarro, Jordi, Puertas, Maria C, Ribas, Bibiana Planas, Rutsaert, Sofie, Salgado, Maria, Torrella, Ariadna, Universitat Autònoma de Barcelona, Urrea, Víctor, Vandekerckhove, Linos   +15 more
core   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Stochastic reservoir computers

Nature Communications
Reservoir computing is a form of machine learning that utilizes nonlinear dynamical systems to perform complex tasks in a cost-effective manner when compared to typical neural networks. Many recent advancements in reservoir computing, in particular quantum reservoir computing, make use of reservoirs that are inherently stochastic.
Peter J. Ehlers, Hendra I. Nurdin, Daniel Soh   +2 more
openaire   +4 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Biological Stoichiometry Regulates Toxin Production in Microcystis aeruginosa (UTEX 2385)

Toxins, 2019
Harmful algal blooms (HABs) are increasing in magnitude, frequency, and duration globally. Even though a limited number of phytoplankton species can be toxic, they are becoming one of the greatest water quality threats to public health and ecosystems due
Nicole D. Wagner, Felicia S. Osburn, Jingyu Wang, Raegyn B. Taylor, Ashlynn R. Boedecker, C. Kevin Chambliss, Bryan W. Brooks, J. Thad Scott   +7 more
doaj   +1 more source

Large-scale Reservoir Simulations on IBM Blue Gene/Q

, 2016
This paper presents our work on simulation of large-scale reservoir models on IBM Blue Gene/Q and studying the scalability of our parallel reservoir simulators. An in-house black oil simulator has been implemented.
H Liu, K Coats, K Coats, K Coats, K Coats, L Zhang, M Christie, Z Chen   +7 more
core   +1 more source