Results 1 to 10 of about 49,444 (266)

Prediction under Uncertainty in Reservoir Modeling [PDF]

open access: yesECMOR VIII - 8th European Conference on the Mathematics of Oil Recovery, 2002
Reservoir simulation is routinely employed in the prediction of reservoir performance under different depletion and operating scenarios. Usually, a single history matched model, conditioned to production data, is obtained. The model is then used to forecast future production profiles.
Subbey, Sam   +2 more
openaire   +4 more sources

Reservoir Analysis And Recovery Prediction For Cycling Gas-Condensate Reservoirs [PDF]

open access: yesFall Meeting of the Society of Petroleum Engineers of AIME, 1965
Publication Rights Reserved This paper was presented at the 40th Annual Fall Meeting of the Society of Petroleum Engineers of AIME, to be held in Denver, Colorado, October 3–6, 1965. Permission to copy is restricted to an abstract of not more than 30 words. Illustrations may not be copied.
O.R. Butterfield   +2 more
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Reservoir Computing as a Tool for Climate Predictability Studies [PDF]

open access: yesJournal of Advances in Modeling Earth Systems, 2021
<p>  Reduced-order dynamical models play a central role in developing our<br>  understanding of predictability of climate irrespective of whether<br>  we are dealing with the actual climate system or surrogate climate<br>  models. In this context,
openaire   +4 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

New approach for compaction prediction in oil reservoirs [PDF]

open access: yesCT&F - Ciencia, Tecnología y Futuro, 2015
As reservoir fluids are produced, pore pressure decreases and compacting rock loses capacity to support the overburden pressure, while the effective stress increases rapidly leading to pore collapse. Reservoir can elastically compact itself until pore pressure drops to the elastic limit, then initiates a plastic deformation known as mechanical ...
Mendoza-Molina, Javier-Fernando   +2 more
openaire   +3 more sources

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