Results 91 to 100 of about 959,404 (311)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Locational choices and the costs of distance: empirical evidence for Dutch graduates [PDF]

open access: yes
This study identifies and analyzes the effects of university/college graduates’ personal, household and employment characteristics as well as the attributes of their study, work and home locations on their college-to-work, college-to-residence, and ...
Carree, Martin, Kronenberg, Kristin
core   +1 more source

Real-time imaging of Leishmania mexicana-infected early phagosomes: a study using primary macrophages generated from green fluorescent protein-Rab5 transgenic mice [PDF]

open access: yes, 2009
The small GTPase Rab5 is a key regulator of endosome/phagosome maturation and in intravesicular infections marks a phagosome stage at which decisions over pathogen replication or destruction are integrated.
Aebischer, Toni   +9 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Black Single Fathers: Choosing to Parent Full-Time [PDF]

open access: yes, 2002
This ethnographic study uses the narratives of African American, single, full-time fathers to explore the motivations precipitating their choice to parent.
Coles, Roberta
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Infestação do Estado de São Paulo por Aedes aegypti e Aedes albopictus

open access: yesRevista de Saúde Pública
OBJETIVO: Estudar a influência da distância entre áreas infestadas e não infestadas na expansão geográfica das populações de Aedes aegypti e de Aedes albopictus no Estado de São Paulo e os padrões regionais observados, considerando os determinantes ...
Carmen Moreno Glasser   +1 more
doaj  

Numerical analysis on the effect of normotensive and hypertensive physiological conditions onto hemodynamic characteristics in stented carotid artery [PDF]

open access: yes, 2019
An arterial re-blockage or restenosis by abnormal atherosclerosis and thrombosis progression in carotid artery is associated with the geometry of the implanted medical device, called as stent.
Ismail, Al Emran   +3 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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