Results 101 to 110 of about 19,131,340 (388)

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Kinetics for Drug Discovery: an industry-driven effort to target drug residence time

Drug Discovery Today, 2017
Doris A. Schuetz, Wilhelmus E. A. de Witte, Yin Cheong Wong, Bernhard Knasmueller, Lars Richter, Daria B. Kokh, S. Kashif Sadiq, Reggie Bosma, Indira Nederpelt, Laura H. Heitman, Elena Segala, Marta Amaral, Dong Guo, Dorothee Andres, Victoria Georgi, Leigh A. Stoddart, Steve Hill, Roger Cooke, Chris de Graaf, Rob Leurs, Matthias Frech, Rebecca C. Wade, Elizabeth C. M. de Lange, Adriaan P. IJzerman, Anke Müller‐Fahrnow, Gerhard F. Ecker   +25 more
openalex   +3 more sources

Fractional time random walk subdiffusion and anomalous transport with finite mean residence times: faster, not slower

, 2012
Continuous time random walk (CTRW) subdiffusion along with the associated fractional Fokker-Planck equation (FFPE) is traditionally based on the premise of random clock with divergent mean period.
A. Chechkin, A. N. Kolmogorov, B. D. Hughes, D. ben-Avraham, I. Goychuk, I. Podlubny, Igor Goychuk, J. Feder, R. Kubo   +8 more
core   +1 more source

Quantum Two-State Dynamics Driven by Stationary Non-Markovian Discrete Noise: Exact Results [PDF]

, 2006
We consider the problem of stochastic averaging of a quantum two-state dynamics driven by non-Markovian, discrete noises of the continuous time random walk type (multistate renewal processes).
Anderson, Ankerhold, Auvergne, Barkai, Barvik, Bittl, Blumen, Brissaud, Burshtein, Burshtein, Chvosta, Cox, Feller, Feynman, Fox, Frisch, Geva, Goychuk, Goychuk, Goychuk, Goychuk, Goychuk, Goychuk, Goychuk, Goychuk, Goychuk, Goychuk, Grifoni, Gutmann, Haken, Haken, Hanggi, Hanggi, Hughes, Hush, Hänggi, Hänggi, Hänggi, Hänggi, Igor Goychuk, Iwaniszewski, Jung, Jung, Kayanuma, Kayanuma, Klyatskin, Kohler, Kraus, Kubo, Kubo, Kubo, Kubo, Lax, Levich, Lindenberg, Lowen, Marcus, May, Metzler, Montroll, Mukamel, Ovchinnikov, Peter Hänggi, Petrov, Petrov, Petrov, Reilly, Reineker, Reineker, Sansom, Shao, Shao, Shapiro, Shapiro, Shlesinger, Slichter, Stehfest, Stehfest, Stockburger, Stratonovich, Valko, Van Kampen, van Kampen, Wiener   +83 more
core   +3 more sources

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

From Mansions to Towers: A History of Residence Halls at the University of Wisconsin-Eau Claire [PDF]

, 2012
The construction of the University of Wisconsin-Eau Claire's residence halls has generally followed that of the national trend. The school struggled to find enough funds to build residence halls in the early years.
Skeen, Mitchell A.
core   +1 more source

Nonchaotic Stagnant Motion in a Marginal Quasiperiodic Gradient System

, 2008
A one-dimensional dynamical system with a marginal quasiperiodic gradient is presented as a mathematical extension of a nonuniform oscillator. The system exhibits a nonchaotic stagnant motion, which is reminiscent of intermittent chaos.
A. Barone, A. M. Rockett, A. T. Winfree, Ch. Nöldeke, D. R. Cox, H. Seifert, P. Bergé, P. Manneville, S. H. Strogatz, T. Akimoto, Takahito Mitsui, V. I. Arnold, Y. Pomeau   +12 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Universality of residence-time distributions in non-adiabatic stochastic resonance [PDF]

, 2004
We present mathematically rigorous expressions for the residence-time and first-passage-time distributions of a periodically forced Brownian particle in a bistable potential.
B Gentz, Benzi R., Berglund N., Berglund N., Day M. V., Day M. V., Eckmann J.-P., Freidlin M. I., Moss F., N Berglund, Nicolis C., Ventcel' A. D., Ventcel' A. D., Wellens T.   +13 more
core   +4 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source