Results 81 to 90 of about 454,936 (308)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Residence time distribution of gas flows in microreactors: Measurement and model comparison
, 2011 This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Blank, T +7 more
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Residence time distributions in laminated microstructured plate reactors
, 2009 This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009) +5 more
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Residence time distribution [PDF]
, 1984 Slurry phase residence time in the SRC-II dissolver is a major process variable affecting the extent of conversion to distillate products. Kinetic studies have shown that overall conversion of vacuum bottoms to lighter hydrocarbons is a zero order process with respect to vacuum bottoms.
openaire +3 more sources
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
The Influence of Residence Time Distribution on Continuous-Flow Polymerization
, 2019 Continuous-flow chemistry is emerging as an enabling technology for the synthesis of precise polymers. Recent advances in this rapidly growing field have hastened a need for a fundamental understanding of how fluid dynamics in tubular reactors influence ...
Frank A. Leibfarth (675326) +11 more
core +1 more source
Hydrogen and Carbon Production via Methane Thermal Decomposition: Effects of Temperature and Residence Time [PDF]
한국정밀공학회지Methane thermal decomposition is a promising technology for producing CO2-free hydrogen. This study experimentally examines how temperature (1,000–1,400oC) and residence time affect methane decomposition in a ceramic tubular reactor.
Mun Hee Lee +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Classification of Animal Movement Behavior through Residence in Space and Time
Identification and classification of behavior states in animal movement data can be complex, temporally biased, time-intensive, scale-dependent, and unstandardized across studies and taxa.
Torres, Leigh G. +3 more
core +1 more source