Results 81 to 90 of about 15,038,060 (290)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
From Mansions to Towers: A History of Residence Halls at the University of Wisconsin-Eau Claire [PDF]
, 2012 The construction of the University of Wisconsin-Eau Claire's residence halls has generally followed that of the national trend. The school struggled to find enough funds to build residence halls in the early years.
Skeen, Mitchell A.
core
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
, 2017 The duration of drug efficacy in vivo is a key aspect primarily addressed during the lead optimization phase of drug discovery. Hence, the availability of robust computational approaches that can predict the residence time of a compound at its target ...
Andrea Rizzi (1845439) +6 more
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Shiyou jixie, 2022 In order to analyze the migration trajectory of discrete oil droplets in coalescer and the influence of coalescer flow field characteristics on oil droplet coalescence,PBM-DPM coupled numerical simulation method was used to obtain the distribution law of
Xing Lei +4 more
doaj
Changes in post-marital residence precede changes In descent systems in Austronesian societies [PDF]
, 2007 Descent systems express how a society organises kinship relationships. Inheritance of resources as well as rights and obligations can be traced patrilineally, matrilineally, a combination of both, or in a cognatic/bilateral fashion.
Jordan, Fiona M +3 more
core
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Frontiers in Marine Science, 2019 Pervasive and sustained coral diseases contribute to the systemic degradation of reef ecosystems, however, to date an understanding of the physicochemical controls on a coral disease event is still largely lacking.
Ferdinand K. J. Oberle +9 more
doaj +1 more source