Results 61 to 70 of about 454,936 (308)

A New Mathematical Numerical Model to Evaluate the Risk of Thrombosis in Three Clinical Ventricular Assist Devices

open access: yesBioengineering, 2022
(1) Background: Thrombosis is the main complication in patients supported with ventricular assist devices (VAD). Models that accurately predict the risk of thrombus formation in VADs are still lacking.
Yuan Li   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Metadynamics Simulations Distinguish Short- and Long-Residence-Time Inhibitors of Cyclin-Dependent Kinase 8

open access: yes, 2017
The duration of drug efficacy in vivo is a key aspect primarily addressed during the lead optimization phase of drug discovery. Hence, the availability of robust computational approaches that can predict the residence time of a compound at its target ...
Andrea Rizzi (1845439)   +6 more
core   +1 more source

Free-time Residence Barometer 2021

open access: yes, 2022
Mökkibarometri on mökkeilyn ja vapaa-ajan asumisen kehitystä kuvaava seurantatutkimus. Barometri on aiemmin toteutettu vuosina 2003, 2008 ja 2015. Mökkibarometrin 2021 laati maa- ja metsätalousministeriön saaristoasiain neuvottelukunnan toimeksiannosta ...
Natural Resources Institute Finland (Luke)   +1 more
core   +1 more source

Elaboration of the Demulsification Process of W/O Emulsion with Three-Dimensional Electric Spiral Plate-Type Microchannel

open access: yesMicromachines, 2019
Rapid and efficient demulsification (destabilizing of an emulsion) processes of a water in oil (W/O) emulsion were carried out in a three-dimensional electric spiral plate-type microchannel (3D-ESPM).
Zhengdong Ma   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Brunetetal-Residence-ForagingBehavior-PLoSONE

open access: yes, 2019
This file indicates the total number of flowers (residence) visited by bumble bees and honey bees during a full foraging bout in patches of Medicago sativa.
Johanne Brunet (6400688)   +1 more
core   +1 more source

Hydrodynamic and solid residence time distribution in a circulating fluidized bed: experimental and 3D computational study [PDF]

open access: yes, 2008
Vertical profiles of local pressure, horizontal profiles of net vertical solid mass flux, and residence time distributions (RTD) of the solid phase are experimentally assessed in the riser of a small scale cold Circulating Fluidized Bed of 9 m high ...
Simonin, Olivier   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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