Results 101 to 110 of about 9,613 (261)

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

Advanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao, Gabriela Laranjeira Abe, Jun‐Ichi Sasaki, Haruaki Kitagawa, Ririko Tsuboi, Tomoki Kohno, Satoshi Imazato   +6 more
wiley   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Comparative analysis of counter-current and co-current downer reactors using particle image velocimetry and computational particle-fluid dynamics

Chemical Engineering Journal Advances
We investigated the hydrodynamics in co- and counter-current downer operations using particle image velocimetry (PIV) and computational particle fluid dynamics simulations (CPFD).
Talal A. Aldugman, Mengmeng Cui, Abdulrahman Alzailaie, Abdullah Alhareth, Kenneth Langley, Lujain Alfilfil, Khalid Almajnouni, Jorge Gascon, Sigurdur Thoroddsen, Pedro Castaño   +9 more
doaj   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

An Ultrapotent, Ultraeconomical, Antifreeze Polypeptide

Advanced Materials, EarlyView.
Simple and inexpensive polypeptides composed of random copolymers of alanine and glutamic acid are effective antifreezes for applications in foods and biomedicine. The polypeptides, inspired by natural extremophile proteins, inhibit the growth of large ice crystals and prevent damage to sensitive biologics.
Thomas J. McPartlon, Charles T. Osborne, Ke Wang, Rachel E. Detwiler, Konrad Meister, Jessica R. Kramer   +5 more
wiley   +1 more source

The Promise of Solid Lubricants for a Sustainable Future

Advanced Materials, EarlyView.
Lubricants are vital for technology, saving energy and resources. The industry seeks sustainable solutions beyond fossil fuels. Solid lubricants offer extremely low friction and reduce environmental impact, especially in harsh conditions. Can these solids truly replace liquid lubricants, or are they limited to extreme applications?
Philipp G. Grützmacher, Andrey A. Voevodin, András Korényi‐Both, Maria Clelia Righi, Christopher DellaCorte, Nazlim Bagcivan, Ali Erdemir, Carsten Gachot   +7 more
wiley   +1 more source

PiP‐Plex: A Particle‐in‐Particle System for Multiplexed Quantification of Proteins Secreted by Single Cells

Advanced Materials, EarlyView.
Detecting proteins secreted by a single cell while retaining its viability remains challenging. A particles‐in‐particle (PiPs) system made by co‐encapsulating barcoded microparticles (BMPs) with a single cell inside an alginate hydrogel particle is introduced.
Félix Lussier, Byeong‐Ui Moon, Mojra Janta‐Polczynski, Yonatan Morocz, Fabian Svahn, Molly Shen, Ljuboje Lukic, Lidija Malic, Teodor Veres, Andy Ng, David Juncker   +10 more
wiley   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source

Photothermally Powered 3D Microgels Mechanically Regulate Mesenchymal Stem Cells Under Anisotropic Force

Advanced Materials, EarlyView.
The photothermally powered microgel is designed to mechanically train mesenchymal stem cells using spatially patterned exogenous forces in three‐dimensional (3D) workspaces. When microgels are activated selectively via photothermal actuation, locally confined tens of nN forces are exerted on cells, triggering osteogenic differentiation in encapsulated ...
Chen Wang, Nergishan İyisan, Philipp Harder, Valentin H. K. Fell, Viktorija Kozina, Hendrik Dietz, Olivia M. Merkel, Berna Özkale   +7 more
wiley   +1 more source

The Space Within: How Architected Voids Promote Tissue Formation

Advanced Materials, EarlyView.
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou, Isabel B. Hui, Carla Fernandez‐Rico, Marcy Zenobi‐Wong   +3 more
wiley   +1 more source