Results 91 to 100 of about 1,849,228 (313)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Personality traits in resident and migratory warbler species. [PDF]

open access: yes, 2005
Animals are often confronted with environmental challenges and the way in which they cope with these challenges can have important fitness consequences.
Ebert, C.   +4 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Machine Learning to Improve Resident Scheduling: Harnessing Artificial Intelligence to Enhance Resident Wellness

open access: yesJournal of Regional Medical Campuses
Introduction: Excessive resident duty hours (RDH) is a recognized issue with implications for physician well-being and patient safety. A significant component of the RDH concern is on-call duty.
Aazad Abbas   +12 more
doaj   +1 more source

On Beckmann's Dispersed "Interaction City" [PDF]

open access: yes
Beckmann's interaction model has each resident touching base in face-to-face activity with every other resident, per unit time, at the other's residence.
Andrei Bazhanov, John Hartwick
core  

Spoonertoons 2: We\u27re Punning for Resident [PDF]

open access: yes, 2005
Our first Spoonertoons collaboration appeared one year ago, in the August 2004 Word Ways. The positive response was so overwhelming (well, uh, the barista at Don\u27s favorite coffee bar liked Heed the Foamless!
Hauptman, Don, Siergey, Jim
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

ASTRA 90 – Aravind slit lamp and training retinal assessment tool

open access: yesIndian Journal of Ophthalmology
Slit-lamp biomicroscopy using a 90-diopter (90D) lens is a standard technique employed by ophthalmologists for detailed evaluation of the posterior segment.
Vedant Sharma   +2 more
doaj   +1 more source

Building Resident Power and Capacity for Change [PDF]

open access: yes, 2009
An "on the ground" reflection about what it takes for funders to work effective with low-income communities. This report is a set of reflections that began with conversations among fifty people who gathered in Chicago in September of 2008 for Grassroots ...
Kristin Senty, Timothy Saasta
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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