Results 51 to 60 of about 1,838,191 (292)
Modulation of apoprotein E secretion in response to receptor-mediated endocytosis in resident and inflammatory macrophages. [PDF]
, 1984 We have determined the effect of various endocytic ligands on the secretion of ApoE by macrophages. ApoE was a major secreted protein of resident macrophages, but BCG-activated macrophages secreted little ApoE and periodate-elicited macrophages secreted ...
Takemura, R, Werb, Z
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Predicting Validity of Electronic Logbook Software for Success Rate of the Residents in Promotion Exam Mashhad School of Medicine Iran [PDF]
Strides in Development of Medical Education, 2016 Background & Objective: According to the regulations for residents promotion exam fifty percent of score (150 scores) is measured via internal academic evaluation; from which thirty scores are measured using logbook software Considering the importance of
Zeinab Javadi +3 more
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Confins, 2018 Photography plays an important role in the rehabilitation of old urban centers: it offers the opportunity for local actors to claim, promote or denounce public heritage action.
Jacques Galhardo
doaj +1 more source
A Break In the Chain: A Look at Communication Between Resident Advisors the Resident Life Employees Above Them. [PDF]
, 2007 Through past experiences and observations of resident advisors (RAs), resident directors (RDs), and the administrative staff of the Residential Life Department, I have noticed a break in the communication between RAs and Housing Administration.
Levine, Rachel
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Longitudinal Study of Body Mass Index in Young Males and the Transition to Fatherhood. [PDF]
, 2016 Despite a growing understanding that the social determinants of health have an impact on body mass index (BMI), the role of fatherhood on young men's BMI is understudied. This longitudinal study examines BMI in young men over time as they transition from
Adam, Emma K +7 more
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Local Determinants of Crime: Distinguishing between Resident and Non-Resident Offenders [PDF]
The paper revisits the local determinants of crime using a spatial model distinguishing between resident and non-resident offenders. Employing data for German municipalities, the model is estimated by means of a spatial GMM approach. Focusing on resident
Büttner, Thiess, Spengler, Hannes
core +3 more sources