Results 61 to 70 of about 1,838,191 (292)
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Experience of general surgery residents in the common core era. [PDF]
Introduction. Surgical resident training is based on academic learning and hospitalbased practical training. The program and duration are listed by ministerial decree after validation of the national pedagogical committee.
Amel GUEZZI, Sihem ABDELAZIZ
doaj +1 more source
Purpose: In 2020, in response to the emergence and global spread of the disease COVID-19, caused by a new variant of coronavirus 2019-nCoV, the government of India ordered a nationwide lockdown for 21 days, which was then extended to a total of over 50 ...
Deepak Mishra +9 more
doaj +1 more source
Anatomy of a Preservation Deal [PDF]
In 2013, the owner, the Melville Charitable Trust, selected Preservation of Affordable Housing, Inc. (POAH), to leverage investment for capital improvements while ensuring continued housing affordability and increasing resident services. POAH was able to
Mark Treskon, Sara McTarnaghan
core
Adolescent Reproductive Knowledge, Attitudes, and Beliefs and Future Fatherhood. [PDF]
PurposeWith a growing focus on the importance of men's reproductive health, including preconception health, the ways in which young men's knowledge, attitudes, and beliefs (KAB) predict their reproductive paths are understudied.
Adam, Emma K +7 more
core +2 more sources
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Teaching methods used by internal medicine residents on rounds: what works?
Vivek T Kulkarni,1 Sanjay M Salgado,2,3 Stephen R Pelletier,4 Helen M Shields3,5,6 1Division of Cardiovascular Medicine, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA; 2Hospitalist Service, Department of ...
Kulkarni VT +3 more
doaj
Mohammad Alkhamees,1 Meshari A Al-Zahrani,1 Sulaiman Almutairi,1 Hammam Alkanhal,1 Mana Almuhaideb,2 Saad M Abumelha3– 5 1Department of Urology, College of Medicine, Majmaah University, Al-Majmaah, Saudi Arabia; 2College of Medicine, King Saud ...
Alkhamees M +5 more
doaj

