Results 171 to 180 of about 380,472 (352)

Clotrimazole‐loaded PLGA microparticles for local drug delivery to the vagina: Shape does matter

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Clotrimazole‐loaded PLGA microparticles for intravaginal delivery. Abstract Background Intravaginal drug administration is the most promising strategy for treating vaginal infections to protect women's health, such as vulvovaginal candidiasis (VVC). However, conventional vaginal formulations in the clinic face challenges such as drug leakage and low ...
Yanyu Li   +8 more
wiley   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

open access: yesAdvanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia   +10 more
wiley   +1 more source

From Bench to Bulk: Investigating Kinetics, Recyclability, and Scale‐Up of ZIF‐67

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Zeolitic imidazolate framework‐67 (ZIF‐67), a subclass of metal–organic frameworks (MOFs), has garnered considerable attention due to its high surface area, open crystal structure, tunable porosity, and potential applications in gas separation, catalysis, and carbon capture.
Aaush Bhardwaj Singh   +1 more
wiley   +1 more source

“We moved her too soon”: Navigating guilt among adult child and spousal caregivers of persons living with dementia following a move into residential long-term care.

open access: hybrid, 2021
Tamara L. Statz   +7 more
openalex   +1 more source

Thermal Calculations for Co‐Firing of Hydrogen/Ammonia and Coal in 660‐MW Coal‐Fired Boilers

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT To achieve a clean energy transition under the dual carbon goals, blending hydrogen/ammonia into pulverized coal boilers represents a key technological pathway. Different hydrogen/ammonia co‐firing ratios (5%–50%) are investigated for their impact on the thermodynamic characteristics of 660‐MW supercritical boiler at 100% and 20% boiler ...
Yaodong Da   +7 more
wiley   +1 more source

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

open access: yesThe Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose   +2 more
wiley   +1 more source

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