Results 181 to 190 of about 5,804,581 (275)

Absorption, distribution, metabolism and excretion of londamocitinib after single‐dose inhaled, intravenous and oral administration in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim Londamocitinib (AZD4604) is an inhaled, selective Janus kinase 1 (JAK1) inhibitor in development for asthma. This open‐label, two‐part, phase I clinical study (NCT06157255) used a radiolabelled microtracer approach to evaluate the absolute bioavailability and the absorption, distribution, metabolism and excretion (ADME) of inhaled londamocitinib ...
Camille Riff, Peter Bold, Maria Heijer, Ryan A. Bragg, Danielle Steele, Tina Jellesmark Jensen, Davinder P. S. Dosanjh, Sabrina I. Hanswijk‐Bartelds, Esther van Duijn, Elwin R. Verheij, Somasekhara Menakuru, Rod Hughes, Helena Dahlbäck   +12 more
wiley   +1 more source

A comparative study of mental health and wellbeing in adopted children, children in foster and kinship care, and the general population. [PDF]

BMC Pediatr
Janes E, Paine AL, Anthony R, Carter B, Shelton KH.   +4 more
europepmc   +1 more source

Practice‐level variation in potentially inappropriate prescribing in middle‐aged adults: A repeated cross‐sectional study in South London general practice

British Journal of Clinical Pharmacology, EarlyView.
Aim To quantify between‐practice variation in potentially inappropriate prescribing (PIP) among middle‐aged adults (45–64 years) in UK general practice, and to identify patient‐ and practice‐level characteristics associated with PIP. Methods Repeated cross‐sectional study using linked data from the Lambeth DataNet and Quality Outcomes Framework across ...
Ryan Jayesinghe, Amandeep Khatter, Stevo Durbaba, Mark Ashworth, Benjamin Jacob, Frank Moriarty, Patrick Redmond   +6 more
wiley   +1 more source

Virtual Reality-Enhanced Training for Trauma-Informed Care Among Residential and Child Mental Health Professionals: Pre-Post Evaluation Study. [PDF]

JMIR Med Educ
Kostadinov K, Goodwin J, Groen G, Jörns-Presentati A, Heffernan S, O'Donovan Á, O'Malley M, Biskupovic Goulding R, O'Mahony J, Allen S, Curtin M, Haapalainen S, Aho J, Petrova G, Ivanova S, Lalova V, Korhonen J.   +16 more
europepmc   +1 more source

Triangulation of dispensing and wastewater data for surveillance during lisdexamfetamine shortages: A descriptive time series analysis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Lisdexamfetamine, a long‐acting stimulant for attention‐deficit hyperactivity disorder (ADHD), has experienced widespread shortages in Australia since late 2023, raising concerns about treatment continuity and shifts in stimulant use patterns.
Jack Janetzki, Emma Keller, Nicole Pratt, Cobus Gerber, Lisa Kalisch Ellett   +4 more
wiley   +1 more source

Post-Traumatic Stress Disorder in Residential Care After an Earthquake: A Follow-Up Study. [PDF]

Noro Psikiyatr Ars
Erbay MF, Karayağmurlu A, Karan P, Soylu N.   +3 more
europepmc   +1 more source

Listening to Hong Kong children's perspectives through pretend play

British Educational Research Journal, EarlyView.
Abstract Quality in early childhood education and care (ECEC) has become an increasing concern in recent years. The issue has been regularly discussed by different stakeholders. However, the rising concern regarding quality in ECEC has not seriously taken into account children's perspectives.
Suzannie K. Y. Leung
wiley   +1 more source

Emergency Department Utilization Patterns and Regional Disparities in Access to Care for Children With Complex Chronic Conditions in Korea: A Nationwide Analysis. [PDF]

J Korean Med Sci
Choi YY, Kim YS, Kim YK, Lee KS, Sung HK.   +4 more
europepmc   +1 more source