Results 31 to 40 of about 1,404,570 (296)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Designing with Care - Interior Design and Residential Child Care Final Report [PDF]
, 2006 This exploratory study examined the attitudes to a range of design interventions in four residential care homes for children in South Lanarkshire. The project set out to identify the benefits and disadvantages to young people and staff of a change in ...
Lerpiniere, Jennifer +3 more
core +4 more sources
Residential care in California
Journal of Maps, 2020 We examine the distribution of residential care in California, showing geographical disparities in care supply and need. We mapped the ratio of beds to older women in Los Angeles and San Diego County census tracts and concentrations of small and large ...
Stephen Frochen +2 more
doaj +1 more source
Land Suitability of Settlements in West Palu District, Palu City [PDF]
E3S Web of Conferences, 2019 A settlement is an important requirement for humans. Increasing the number of residents has encouraged additional needs for residential land while the amount of land has not increased.
Santoso Selamet +2 more
doaj +1 more source
Youth in Residential Facilities: “Am I Safe?,” “Do I Matter?,” and “Do You Care?” [PDF]
, 2022 Youth in residential facilities need to perceive that they are safe. Their perceptions of the quality of treatment and care they receive are affected by how staff behave toward and communication with them as well as by the extent to which they can ...
Slaatto, Ane +3 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah +6 more
wiley +1 more source
Medication charts in residential aged-care facilities [PDF]
Australian Prescriber, 2017 What are the inefficiencies and risks associated with the ordering and supply of drugs in residential aged‑care facilities?
John, Jackson, Elspeth, Welsh
openaire +2 more sources
Arthritis Care &Research, EarlyView.Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok +7 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Ambulatory care–sensitive conditions (ACSCs) serve as indicators of access, quality, and performance of the health system. This study aimed to determine rheumatoid arthritis (RA)‐specific ACSCs for use in the evaluation of care system access and quality.
Kara Irwin +7 more
wiley +1 more source