ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou +9 more
wiley +1 more source
Approach With Caution: A Pilot Randomised Controlled Trial of Approach Bias Modification for People Undergoing Residential Treatment for Methamphetamine Use Disorder. [PDF]
Manning V +9 more
europepmc +1 more source
Parents' Perspectives in Accessing Psychiatric Residential Treatment for Children and Youth: Differential Experiences by Funding Source. [PDF]
Herbell K, Graaf G.
europepmc +1 more source
A deep comprehension of biomolecular phenomena at interfaces is significant with their fundamental and practical importance. Our experimental and theoretical investigations reveal that specific amino acids (glutamic acid and aspartic acid) exhibit an orientational coupling with liquid crystals, which can recognize and optically report the interfacial ...
Yena Choi +10 more
wiley +1 more source
Light‐Harvesting Photothermal Hotspots Enabled by NIR Scattering‐Absorption Coupling
By coupling the broadband scattering of nanodiamonds with the plasmonic absorption of gold nanostars, this work proposes a novel strategy for the active modulation of photon transport. This strategy creates localized photothermal hotspots in turbid media and achieves a supra‐additive heating efficiency, thereby providing a universal platform for low ...
Zebin Wu +17 more
wiley +1 more source
Countercontrol and Associated Challenges in Residential Treatment. [PDF]
O'Neill J, Tacosik J.
europepmc +1 more source
Inflation, real interest tax wedges, and capital formation [PDF]
Inflation magnifies the distorting effects of taxation when the tax treatment of interest income and expense is not fully indexed to inflation. The distortion involves a real interest tax wedge which is the difference between the real before tax interest
William G. Dewald
core
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li +6 more
wiley +1 more source
Medicaid: Increased Patient Access To MOUD In Residential Treatment Associated With Facility Openings And Closures, 2012-22. [PDF]
Beetham T +4 more
europepmc +1 more source
Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao +5 more
wiley +1 more source

