Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation
Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu +8 more
wiley +1 more source
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia +10 more
wiley +1 more source
Parent SMART: Effects of residential treatment and an adjunctive parenting intervention on behavioral health services utilization. [PDF]
Becker SJ +7 more
europepmc +1 more source
Cavity‐Enhanced Eye‐Readable Detection of 0.1% H2 via Active Modulation of Charge‐Transfer Plasmons
A cavity‐structured nanoparticle sensor is developed for highly sensitive, eye‐readable hydrogen detection. Its excellent colorimetric response arises from a hydrogen‐induced charge‐transfer mechanism: reduction of the dielectric oxide shell in H2 triggers a transition from the plasmonic gap mode to the charge‐transfer plasmon mode.
Xuemin Zhang +9 more
wiley +1 more source
Within-person affect dynamics among individuals in residential treatment for opioid use disorder: An ecological momentary assessment study. [PDF]
Knapp KS +5 more
europepmc +1 more source
Designing Tissue Function Through Embedded Bioprinting Architectures
Embedded bioprinting enables soft, cell‐dense constructs to be fabricated within supporting bath environments. This review introduces a function‐guided framework linking target tissue functions to architectural requirements, supporting bath selection, bioink design, printing dynamics, and validation assays.
Qi Li +4 more
wiley +1 more source
Medication Treatment for Youth in Substance Use Disorder Residential Treatment. [PDF]
Yule AM, Mail V, Butler R, Wilens TE.
europepmc +1 more source
Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim +12 more
wiley +1 more source
Adverse Childhood Experiences among Adolescent Girls in Residential Treatment: Relationship with Trauma Symptoms, Substance Use, and Delinquency. [PDF]
Mii AE +6 more
europepmc +1 more source

