Results 231 to 240 of about 4,236,198 (272)

Bevacizumab's role in advanced ovarian clear cell carcinoma warrants more detailed analyses. [PDF]

J Gynecol Oncol
Huang KJ.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

A variational framework for residual-based adaptivity in neural PDE solvers and operator learning. [PDF]

NPJ Artif Intell
Toscano JD, Chen DT, Ooomen V, Darbon J, Karniadakis GE.   +4 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Histopathological evaluation of local effects of radioactive iodine seeds in axillary lymph nodes in clinically node-positive breast cancer treated with neoadjuvant systemic therapy. [PDF]

Breast
van Amstel FJG, Simons JM, Kooreman L, Lenaerts M, van Kuijk SMJ, Murrer LHP, de Mooij CM, Luiten EJT, van der Pol CC, Koppert LB, Smidt ML, van Diest PJ, van Nijnatten TJA, REFINE Study Group.   +13 more
europepmc   +1 more source

Effects of nitrogen fertilizer rates on nutrient uptake, vertical nutrient distribution, and nitrogen balance in dryland spring wheat. [PDF]

Front Plant Sci
Xu A, Khan KS, Zhang Y, Liu N, Liu P, Chen Y, Wei X, Sun C, Effah Z, Li L.   +9 more
europepmc   +1 more source

Investigating the impact of residual refraction within ±1.0 dioptre on uncorrected distance visual acuity in pseudophakic eyes: a cross-sectional study. [PDF]

BMJ Open
Li D, Zhang J, Jin L, Han X, Chen L, Liu Y, Cai W, Cao Q.   +7 more
europepmc   +1 more source

Impact of Monomer Selection and Behavior on Transdermal Drug Delivery Systems: Regulatory and Formulation Perspectives. [PDF]

Cureus
Modi P, Modasiya J, Desai D.
europepmc   +1 more source