Results 201 to 210 of about 17,083 (261)

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

A dual-interface load transfer model for precast concrete-cored cemented soil piles considering progressive damage. [PDF]

PLoS One
Liang H, Zhu Y, Xu L, Wu H, Zhang J, Xu B, Cao K.   +6 more
europepmc   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

FISH-Dist: An Automated Pipeline for 3D Genomic Spatial Distance Quantification in FISH Imaging. [PDF]

Bioengineering (Basel)
Aigouy B, Caturegli E, Charroux B, Martins CS, Gregor T, Prud'homme B.   +5 more
europepmc   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Sound-evoked tonic motility of cochlear outer hair cells in mice with stereociliary defects. [PDF]

Proc Natl Acad Sci U S A
Dewey JB.
europepmc   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Fault-mediated magma propagation and triggered seismicity revealed by the 2022 São Jorge Azores unrest. [PDF]

Nat Commun
Hicks SP, Gonzalez PJ, Lomax A, Ferreira AMG, Ramalho RS, Mitchell NC, Silveira G, Dias NA, Fontiela J, Fernandes R, Custódio S, Tsekhmistrenko M, Mendes V, Pimentel A, Silva R, Prates G, Sturgeon W, Marignier A, Carrilho F, Marques R, Miranda M, Garcia AM.   +21 more
europepmc   +1 more source

Integrated Dynamic Modeling and Ground Test Validation for Spacecraft Micro-Vibration Suppression Considering Disturbance, Isolation, and Pointing Control. [PDF]

Sensors (Basel)
Wang H, Yan H, Tian L, Zang X, Zu Y.
europepmc   +1 more source

CRR-Net: a correlation reconstruction and refinement network for deformable medical image registration. [PDF]

Vis Comput Ind Biomed Art
Xie B, Zhang G, Xu K.
europepmc   +1 more source