Results 71 to 80 of about 1,979,413 (280)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Development of methodology for measurements of residual stresses in welded joint based on displacement of points in a coordinated table

Materials Research, 2013
Residual stresses in a welded joint of ASTM A131 grade AH32 steel was measured either by the X-ray diffraction or by displacements of referenced points measured on a coordinate measuring machine before and after heat treatment. For all tests, the welding
Aníbal Veras Siqueira Filho, Tiago Leite Rolim, Yogendra Prasad Yadava, Francisco Ilo Bezerra Cardoso, Pablo Batista Guimarães, Theophilo Moura Maciel, Ricardo Artur Sanguinetti Ferreira   +6 more
doaj  

Evaluating Lateral Spreading Using Newmark Method Based on Liquefaction Triggering

Advances in Civil Engineering, 2020
The prediction of liquefaction-induced lateral spreading is an important geotechnical engineering problem. In this paper, a simplified prediction method based upon Newmark sliding block analysis was proposed to predict the liquefaction-induced lateral ...
Yanxin Yang, Junhua Chen, Zhenqiang Zhang, Jianlin Ma   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Development of a magnetic composite material for measurement of residual limb displacements in prosthetic sockets

Journal of Rehabilitation and Assistive Technologies Engineering, 2018
Introduction Wearable limb–socket displacement sensors may help patients and prosthetists identify a deteriorating socket fit and justify the need for repair or replacement.
Ethan J Weathersby, John C Cagle, Brian G Larsen, Katrina M Henrikson, Joan E Sanders   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Digital Image Correlation for Elastic Strain Evaluation during Focused Ion Beam Ring-Core Milling

Journal of Manufacturing and Materials Processing
This paper details the utilization of the focused ion beam digital image correlation (FIB-DIC) technique for measuring in-plane displacements and the employment of the height digital image correlation (hDIC) technique as a two-step DIC method for ...
Fatih Uzun, Alexander M. Korsunsky
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Experimental Investigation of Granular Soil and Clay Interfaces with Direct Shear Tests

Geotechnics
This study experimentally investigates the shear strength behavior of interfaces formed between granular soils and clay under drained conditions, with particular emphasis on peak-to-residual strength evolution.
Sevki Ozturk, Mehmet Ufuk Ergun
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source