Design of a Synergistic Active-Passive Shielding System Using Fe-Based Amorphous Alloy. [PDF]
Zhu X, Lu L, Zhang G, Jiang J.
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Particle background characterization and prediction for the NUCLEUS reactor CE ν NS experiment. [PDF]
Abele H +59 more
europepmc +1 more source
Methods for Determining the Residual Flux in a Magnetic Core
Remanentni tok u magnetskoj jezgri može stvarati značajne probleme u radu elektroenergetskog sustava, posebice pri uklopu transformatora na nazivni napon. U praksi ga je nemoguće izravno mjeriti s obzirom da je zatvoren unutar jezgre. Iako postoje metode koje ga neizravno određuju, zbog njihovih nedostataka javlja se potreba za razvojem novih koje će ...
openaire +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Comparative human and porcine skin permeation profiles of novel metformin lotion formulations. [PDF]
Zhao C +4 more
europepmc +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
A Variational Formulation for Irreversible Thermodynamics with Path Dependence. [PDF]
Ren H.
europepmc +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
<i>De novo</i> synthesis of L-2-aminobutyric acid in <i>Escherichia coli</i> based on multi-layered metabolic engineering strategies. [PDF]
Zhao Z +8 more
europepmc +1 more source

