Results 191 to 200 of about 390,638 (295)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Design of a Synergistic Active-Passive Shielding System Using Fe-Based Amorphous Alloy. [PDF]

ACS Omega
Zhu X, Lu L, Zhang G, Jiang J.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Membrane Separation Techniques: Advances, Challenges, and Future Avenues. [PDF]

Membranes (Basel)
Ho CD.
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Comparative human and porcine skin permeation profiles of novel metformin lotion formulations. [PDF]

Sci Rep
Zhao C, Zhang J, Pastukh V, Ejaz A, Wang JH.   +4 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Particle background characterization and prediction for the NUCLEUS reactor CE ν NS experiment. [PDF]

Eur Phys J C Part Fields
Abele H, Angloher G, Arnold B, Corona MA, Bento A, Bossio E, Buchsteiner F, Burkhart J, Cappella F, Cappelli M, Casali N, Cerulli R, Cruciani A, Del Castello G, Del Gallo Roccagiovine M, Dorer S, Erhart A, Friedl M, Fichtinger S, Ghete VM, Giammei M, Goupy C, Hauff D, Jeanneau F, Jericha E, Kaznacheeva M, Kluck H, Langenkämper A, Lasserre T, Lhuillier D, Mancuso M, Martin R, Mauri B, Mazzolari A, McCallin L, Neyrial H, Nones C, Oberauer L, Ortmann T, Peters L, Petricca F, Potzel W, Pröbst F, Pucci F, Reindl F, Romagnoni M, Rothe J, Schermer N, Schieck J, Schönert S, Schwertner C, Scola L, Soum-Sidikov G, Stodolsky L, Strauss R, Thalmeier R, Tomei C, Vignati M, Vivier M, Wex A.   +59 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

A Variational Formulation for Irreversible Thermodynamics with Path Dependence. [PDF]

Entropy (Basel)
Ren H.
europepmc   +1 more source