Results 51 to 60 of about 1,252,987 (207)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Synchrotron strain scanning for residual stress measurement in cold-drawn steel rods [PDF]

, 2011
Cold-drawn steel rods and wires retain significant residual stresses as a consequence of the manufacturing process. These residual stresses are known to be detrimental for the mechanical properties of the wires and their durability in aggressive ...
M Elices, J Ruiz-Hervias, Elices Calafat, Manuel, Ruiz Hervías, Jesús, Atienza Riera, José Miguel, J M Atienza   +5 more
core   +1 more source

Phy-Flux/Convection-permitting-EPS-Up-scaling-: UpS_algorithms

, 2021
The code provides two alternative algorithms for the Up-scaling of atmospherical scalar field ...
Phy-Flux
core   +1 more source

Heat treatment of crushed oil seeds sunflower before pressing [PDF]

E3S Web of Conferences
The work investigates the process of preliminary heat treatment of oilcake of sunflower variety Dushko in the field of infrared irradiation before pressing. Based on the planning of experiments, a pattern of changes in the value of the output parameter -
Gafurov Karim, Safarova Dilshoda, Akabirova Lola, Sharipov Nodirjon, Kuldosheva Firuza, Yamaletdinova Munira   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Weld residual stress effects on fatigue crack growth behaviour of aluminium alloy 2024-T351 [PDF]

, 2008
The interaction between residual stress and fatigue crack growth rate has been investigated in middle tension and compact tension specimens machined from a variable polarity plasma arc welded aluminium alloy 2024-T351 plate.
Liljedahl, CDM, Tan, M. L., Edwards, Lyndon, Irving, PE, Brouard, J, Liljedahl, C.D.M., Zanellato, O., Fitzpatrick, M. E., Zhang, Xiang, Fitzpatrick, M.E., Brouard, J., Ganguly, S, Liljedahl, C. David M., Ganguly, S., Zanellato, O, Irving, P.E., Lin, J., Tan, ML, Liljedahl, C. D. M., Edwards, L., Fitzpatrick, Michael E., Zhang, X.; id_orcid, Ganguly, Supriyo, Zhang, X., Zhang, X, Edwards, L, Zanellato, Oliver, Lin, J, Irving, P. E., Irving, Phil E., Tan, M.L., Fitzpatrick, ME   +31 more
core   +1 more source

Mitigating the Inrush Current of V/V Transformers Using Railway Conditioners

IEEE Access
Inrush current is high-magnitude current drawn by power transformers upon energization. The severity of inrush current depends on factors such as the transformer’s residual flux and the voltage phase angle at the energization instant.
Amir Aghazadeh, Ehsan Hajipour, Kang Li, Sadegh Azizi   +3 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

An inverse method for evaluating weld residual stresses via fatigue crack growth test data [PDF]

, 2010
This paper presents an inverse method for calculating the thermal residual stresses in welded specimens via measured fatigue crack growth rates. Firstly, fracture-mechanics superposition law has been used to extract the stress intensity factor due to ...
Rui Bao, Xiang Zhang, Bao, Rui, Zhang, Xiang   +3 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source