Results 81 to 90 of about 70,444 (281)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Finite Element Analysis of Residual-Stress-Based Flux Barriers on the Performance of PMSMs

open access: yes
This paper investigates the impact of residual-stress-based flux barriers on the performance of permanent magnet synchronous machines (PMSMs) by using finite element analysis. In contrast to conventional cutout-based flux barriers, which improve magnetic
Douiri, Achref   +7 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Analysis of cylindrically and spherically embossed flux barriers in non-oriented electrical steel

open access: yes, 2020
In reluctance and permanent magnet synchronous machines, flux barriers are crucial for magnetic flux guidance. Designed as cutouts, flux barriers reduce the mechanical strength of the rotor construction.
Hameyer, Kay   +8 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

SIMULATION OF HYBRID LASER-TIG WELDING PROCESS USING FEA [PDF]

open access: yesJournal of Engineering Science and Technology, 2018
Hybrid welding technology has wide advantages in welding to improve speed, weldability of special materials, increasing depth of weld. Less defects of the weld, less bead widths, less temperature, less distortion and less residual stresses are seen.
HARINADH VEMANABOINA   +3 more
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Effect of Carbon and TiO₂ on Fluidity of Mold Flux

open access: yesTeshugang, 2006
The effect of C content(8.39%~14.20%)and TiO₂(0.35%) on fluidity of mold flux-21.98~ 27.93 CaO,32.03~43.20 SiO₂,4.58~5.83 Al₂O₃ at 1120~1200℃has been studied.The results showed that residual carbon in flux and TiO₂ in flux which was produced by Ti ...
武守防, 李宏, 王恭亮, 梁玫
doaj  

Effects of heat treatment processes on microstructural evolution and magnetic properties in medium-carbon low-alloy semi-hard magnetic steels

open access: yesCailiao gongcheng
To obtain Fe-based medium-carbon low-alloy semi-hard magnetic steels with high residual magnetic flux density Br, five distinct heat treatment processes are employed: full annealing, air quenching (AQ), water quenching (WQ), air quenching followed by ...
LI Jun   +5 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

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