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Asymptotic Solutions of Time-Space Fractional Coupled Systems by Residual Power Series Method [PDF]

Discrete Dynamics in Nature and Society, 2017
This paper focuses on the asymptotic solutions to time-space fractional coupled systems, where the fractional derivative and integral are described in the sense of Caputo derivative and Riemann-Liouville integral. We introduce the Residual Power Series (for short RPS) method to construct the desired asymptotic solutions.
Wenjin Li, Yanni Pang
openaire   +3 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Approximate Analytical Solutions for Strongly Coupled Systems of Singularly Perturbed Convection–Diffusion Problems

Mathematics
This work presents a reliable algorithm to obtain approximate analytical solutions for a strongly coupled system of singularly perturbed convection–diffusion problems, which exhibit a boundary layer at one end. The proposed method involves constructing a
Essam R. El-Zahar, Ghaliah F. Al-Boqami, Haifa S. Al-Juaydi   +2 more
doaj   +1 more source

Numerical Algorithm for Nonlinear Delayed Differential Systems of $n$th Order

, 2019
The purpose of this paper is to propose a semi-analytical technique convenient for numerical approximation of solutions of the initial value problem for $p$-dimensional delayed and neutral differential systems with constant, proportional and time varying
Rebenda, Josef, Šmarda, Zdeněk
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

A Numerical Solution of Fractional Lienard’s Equation by Using the Residual Power Series Method

Mathematics, 2017
In this paper, we investigate a numerical solution of Lienard’s equation. The residual power series (RPS) method is implemented to find an approximate solution to this problem.
Muhammed I. Syam
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Fractional analysis of non-linear fuzzy partial differential equations by using a direct procedure

Scientific Reports
In this study, an accurate analytical solution is presented for fuzzy FPDEs. It is done by using a novel method called the Laplace-residual power series (LRPSM) to build a series solution to the given problems. The fundamental instruments of the employed
Muhammad Arshad, Shahbaz Khan, Hassan Khan, Hamid Ali, Ijaz Ali   +4 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source