Results 51 to 60 of about 3,224 (230)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

On the Laplace Residual Series Method and Its Application to Time-Fractional Fisher’s Equations

open access: yesFractal and Fractional
In this paper, we develop an analytical approximate solution for the nonlinear time-fractional Fisher’s equation using a right starting space function and a unique analytic-numeric technique referred to as the Laplace residual power series approach.
Rawya Al-deiakeh   +4 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Solving Boundary-Layer Problems by Residual-Power-Series Method

open access: yesJournal of Mathematics Research, 2016
<p><span lang="EN-US">In this paper, the so-called residual-power-series (RPS) method is presented for solving nonlinear boundary-layer equations. The RPS method provides a single unified treatment for the linear and nonlinear terms in the equations.
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Solution of Fractional SIR Epidemic Model Using Residual Power Series Method

open access: yes, 2019
The SIR model with unknown parameters is an important issue for scientists in the study of epidemiology and medical care for the injured people. In this work, an efficient technique based on the generalized Taylor series, called the residual power series
Freihet, Asad   +4 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Approximate Analytical Solutions for Strongly Coupled Systems of Singularly Perturbed Convection–Diffusion Problems

open access: yesMathematics
This work presents a reliable algorithm to obtain approximate analytical solutions for a strongly coupled system of singularly perturbed convection–diffusion problems, which exhibit a boundary layer at one end. The proposed method involves constructing a
Essam R. El-Zahar   +2 more
doaj   +1 more source

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