Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Effect of Water Film Induced by Wet Shot Peening on Dimple Size and Residual Stress Distribution. [PDF]
Fang C, Wang Z.
europepmc +1 more source
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić +3 more
wiley +1 more source
Experimental and Simulation Study on Residual Stress of Pure Copper Welded Joint by Laser Shock Peening. [PDF]
Ma Y, Li S, Tang Y, Zhang Y.
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Controlling Residual Stress and Microstructure Distribution in an Invar Alloy Joint Fabricated by Oscillating Laser Welding. [PDF]
Jiang Y +5 more
europepmc +1 more source
Non-destructive measurement of residual stresses in welded aluminium 2024 airframe alloy
Supriyo Ganguly
openalex +1 more source
Geometrical effects on residual stress in selective laser melting
L. Parry, I. Ashcroft, R. Wildman
semanticscholar +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source

