Results 121 to 130 of about 61,819 (240)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Biomechanical contributions to murine lens shape: Confinement, compaction, and residual stresses. [PDF]

Exp Eye Res
Reilly MA.
europepmc   +1 more source

Numerical Study on Residual Stresses and Plastic Strains in Cold-Formed High-Strength Steel Circular Hollow Sections. [PDF]

Materials (Basel), 2023
Yao Y, Quach WM.
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Experimental data on the generation of compressive residual stresses via shot peening and subsequent heat treatment in SAE 5160 and DIN 51CrV4 spring steels. [PDF]

Data Brief
Pereira Dos Santos M, Farias A, Bordinassi EC, Delijaicov S.   +3 more
europepmc   +1 more source

Quantification and Analysis of Residual Stresses in Braking Pedal Produced via Laser-Powder Bed Fusion Additive Manufacturing Technology. [PDF]

Materials (Basel), 2023
Fojtík F, Potrok R, Hajnyš J, Ma QP, Kudrna L, Měsíček J.   +5 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Mapping residual stresses in AlSi10Mg alloy fabricated by powder bed fusion-laser beam method. [PDF]

Sci Rep
Daoud ME, Taha I, Abdelgawad A, Barsoum I, Khan KA, Anjum DH.   +5 more
europepmc   +1 more source

On the Residual Stresses and Fracture Toughness of Glass/Carbon Epoxy Composites. [PDF]

Materials (Basel), 2022
Umarfarooq MA, Gouda PSS, Banapurmath NR, Kittur MI, Khan T, Badruddin IA, Kamangar S, Hussien M.   +7 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source