Results 81 to 90 of about 1,022,224 (293)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Residual Stresses in Dengeling-Treated Aluminum Alloy AA 7050

open access: yes, 2017
Dengeling is a new method for mechanical surface treatment of metallic parts to enhance fatigue properties. The treatment produces consecutive lines of indents by a spherical indenter, resulting in compressive residual stresses in a surface layer.
Petersén, Gert,   +5 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Proposal of residual stress mitigation in nuclear safety-related austenitic stainless steel TP304 pipe bended by local induction heating process via elastic-plastic finite element analysis

open access: yesNuclear Engineering and Technology, 2019
This paper proposes a residual stress mitigation of a nuclear safety-related austenitic stainless steel TP304 pipe bended by local induction heating process via performing elastic-plastic finite element analysis. Residual stress distributions of the pipe
Jong-Sung Kim   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

3D Residual Stresses in Selective Laser Melted Hastelloy X

open access: yes, 2017
3D residual stresses in as manufactured EOS NickelAlloy HX, produced by laser powder bed additive manufacturing, are analysed on the surface closest to the build-plate.
Saarimäki, Jonas,   +3 more
core   +1 more source

On Residual Stresses in Arteries [PDF]

open access: yesJournal of Biomechanical Engineering, 1986
C J, Chuong, Y C, Fung
openaire   +2 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

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