Rethinking peptide developability with sequence-only models: interpretable screening of microplastic-binding peptides with gated query pooling. [PDF]
Chen G, You F.
europepmc +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
A Circular Material Value Retention Framework for Agricultural By-Product Valorisation. [PDF]
Alizad R, Haddad Y, Salonitis K.
europepmc +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Interactions and Conformational Plasticity of Human Uncoupling Protein 1 in Response to Small-Molecule Analogues: Insights from Molecular Dynamics Simulations. [PDF]
Rathod S +4 more
europepmc +1 more source
KOHNUMA, Shigeyoshi +2 more
openaire +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Restoring soil functionality and improving wheat yield through integrated farmyard manure, compost, crop residues and decomposition enhancers. [PDF]
Kalim M +7 more
europepmc +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
An <i>In silico</i> analysis on the phosphorylation dependent structural and thermal stability of thermophilic proteins. [PDF]
Arunachalam S, Gnanasekaran R.
europepmc +1 more source

