Results 121 to 130 of about 663,482 (304)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Pesticide residue detection techniques for increasing productivity and yield: recent progress and future outlooks

open access: yesFrontiers in Plant Science
The intensive use of pesticides in modern agriculture has significantly improved crop yield and food security but introduced serious health concerns due to the accumulation of pesticide residues in fruits and vegetables and the environment, posing ...
Muhammad Umer   +13 more
doaj   +1 more source

SINTESI E PROPRIETA’ BIOLOGICHE DI LIGANDI GLICOSIDICI MULTIVALENTI [PDF]

open access: yes, 2009
Protein-carbohydrate interactions are at the heart of many important biological processes as the adesion of bacteria and viruses to the cell surfaces.
Moni, Lisa
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The Comparison of Doxycycline Residue in the Meat of Broiler Chickens Administered in Feed and Water

open access: yesMedia Peternakan, 2011
The purpose of this research was to investigate the effect of doxycycline (a tetracycline derivative) administered at disease-prevention dose given daily in the feed and drinking water on the residue level in the broiler-chicken meat.
A. D. Wijayanti   +2 more
doaj  

SAR Studies on the Inhibitors for the Treatment of Inflammatory Diseases [PDF]

open access: yes, 2016
School of Molecular Sciences(Chemistry)Inflammation is defensive host response that occurs from infection and injury and the inflammatory process is the pivotal physiological response of our body and essential part of the human physiology.
Kim, Min-Jeong
core  

Studies on the residue chemistry of some organophosphorus pesticides [PDF]

open access: yes, 1987
The plan of working has involved synthetic organic chemistry and analytical chemistry related to specific studies on two organophosphorus pesticides, viz. Q, Q-diethyl -(K-ethosycarbonyl-8-methylcarbamoylmethyl) phosphorodithioate (common name mecarbam) and 0, G-diethyl S-chloromethyl phosphorodithioate (common name chlormephos).
openaire   +1 more source

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