Results 111 to 120 of about 2,876,597 (260)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Can inorganic fertilizer substitute for organic amendments in the rehabilitation of saline, sodic ore refining residues? [PDF]

, 2003
Organic amendments would generally be attractive additions for revegetation of ore refining residues that mostly contain negligible organic matter. However organic materials may not be available on mine sites in sufficient quantities and are bulky to ...
Fletcher, N., Bell, R.W., Krockenberger, I., Samaraweera, M.K.S.A.   +3 more
core  

Solution coordination chemistry of actinides: Thermodynamics, structure and reaction mechanisms

, 2006
31 pagesThe emphasis of this review is on the combination of experimental and theoretical methods to obtain microscopic information on the chemistry of actinides in aqueous solution. A brief discussion is given of some important experimental methods that
Toraishi, Takashi, Toraishi, T., Szabó, Zoltan, Vallet, Valérie, Grenthe, I., Grenthe, Ingmar, Vallet, V., Szabo, Zoltan,   +7 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

The Residue Chemistry Transformation Linked to the Fungi Keystone Taxa during Different Residue Tissues Incorporation into Mollisols in Northeast China

Agriculture
Managing carbon input from crop straw in cropland ecosystems could increase soil organic carbon (SOC) sequestration to achieve C neutrality and mitigate climate change.
Qilin Zhang, Xiujun Li, Guoshuang Chen, Nana Luo, Jing Sun, Ezemaduka Anastasia Ngozi, Xinrui Lu   +6 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Dynamics underlie the drug recognition mechanism by the efflux transporter EmrE

Nature Communications
The multidrug efflux transporter EmrE from Escherichia coli requires anionic residues in the substrate binding pocket for coupling drug transport with the proton motive force. Here, we show how protonation of a single membrane embedded glutamate residue (
Jianping Li, Ampon Sae Her, Alida Besch, Belen Ramirez-Cordero, Maureen Crames, James R. Banigan, Casey Mueller, William M. Marsiglia, Yingkai Zhang, Nathaniel J. Traaseth   +9 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Chemistry and Biochemistry at Texas, 1990

, 1990
Table of Contents: The City and the Region (p. 1) -- The University (p. 3) -- The Department (p. 4) -- The Mallet Library (p. 5) -- X-Ray Diffraction Facility (p. 6) -- NMR Facility (p. 7) -- Mass Spectroscopy Facility (p. 8) -- Computer Facilities (p. 9)
Chemistry Department
core   +1 more source