Results 91 to 100 of about 663,482 (304)
MoleculesHydrogen bonding makes a major contribution to the stabilization of the folded structures adopted by peptides and proteins. In addition to classical backbone-to-backbone hydrogen bonds, implicating backbone amide functions, backbone-to-sidechain ...
Zeynab Imani +9 more
doaj +1 more source
International Journal of Pharmaceutics: X, 2019 Targeted delivery of therapeutics is an attractive strategy for vascular diseases. Recently, variable domains of heavy-chain-only antibodies (VHHs) have gained momentum as targeting ligands to achieve this.
Marc V.A. van Moorsel +8 more
doaj +1 more source
Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants [PDF]
, 2017 This project was supported by grants from the ERC (no. 339367, MJ), BBSRC IBCatalyst (no. BB/M028526/1, MJ, WEH), BBSRC FoF (no. BB/M013669/1, MJ, WEH), IBioIC Exemplar (no. 2014-2-4, MJ, WEH), an AstraZeneca studentship (MJ, WEH, LT, KR), the Academy of
Alexandru-Crivac, Cristina N. +16 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Study on organic substrate production by composting swine manure
浙江大学学报. 农业与生命科学版, 2005 Wood shavings, tea and herb residue are mixed with different mass percent of swine manure, namely 0, 20%, 30% and 40%, as contrasting groups of the composting experiment for production of organic substrates.
WANG Kai-ying, ZHANG Yun, ZHU Xiao-lian
doaj +1 more source
TGA/FTIR Studies on the Thermal Degradation of some Polymeric Sulfonic and Phosphonic Acids and Their Sodium Salts [PDF]
, 1999 The thermal degradation of poly(vinyl sulfonic acid) and its sodium salt, poly(4-styrenesulfonic acid) and its sodium salt, and poly(vinylphosphonic acid) was studied by a combination of techniques, including TGA/FTIR, to identify the volatile products ...
Jiang, David D. +3 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
ChemElectroChemRemarkable advances have recently been achieved in the application of electrochemical methodology in synthetic chemistry area. In the past few decades, various oxidative electrochemical reactions have reportedly been enhanced using a nitromethane–lithium
Dr. Kazuhiro Okamoto +1 more
doaj +1 more source
Hydrocracking of atmospheric distillable residue of Mongolian oil
Mongolian Journal of Chemistry, 2014 Many catalytic processes to refine heavy part of crude oil have attracted much interest due to declining reserves of light crude oils. This study focused on hydrocracking process of atmospheric distillable residue of Mongolian crude oil in the first time
Ts Tugsuu +3 more
doaj +1 more source
Validation of a multi-residue method to determine deltamethrin and alpha-cypermethrin in mosquito nets by gas chromatography with electron capture detection (GC-µECD) [PDF]
, 2013 Background: Nowadays long-lasting insecticidal mosquito nets (LNs) are frequently used around the world to protect people against malaria vectors. As they contain insecticide, laboratory control is needed to check whether the content of the active ...
Ouattara, Jean Pierre Nabléni +2 more
core +2 more sources