Results 71 to 80 of about 663,482 (304)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Candidate amino acids involved in H+ gating of acid-sensing ion channel 1a [PDF]
Acid-sensing ion channels are ligand-gated cation channels, gated by extracellular H+. H+ is the simplest ligand possible, and whereas for larger ligands that gate ion channels complex binding sites in the three-dimensional structure of the proteins have
Chen, Xuanmao +4 more
core +1 more source
Infrared Techniques Useful in Residue Chemistry
Abstract Although infrared spectrophotometry is suitable for the measurement and identification of pesticides and their metabolic products because of its inherent characterizing properties, only recently have techniques and instrumentation become adequate for the difficult requirements of residue chemistry.
openaire +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Pesticides and Trace Element Residues in Honey from Northern Croatia
The rapid translocation of pesticide and metal residues in the environment and their entry into the food chain pose a significant risk to human health.
Damir Pavliček +7 more
doaj +1 more source
Development of Peptoid-Based Ligands for the Removal of Cadmium from Biological Media. [PDF]
Cadmium poisoning poses a serious health concern due to cadmiums increasing industrial use, yet there is currently no recommended treatment. The selective coordination of cadmium in a biological environment-i.e.
Francis, Matthew +2 more
core +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Water pollution by antibiotic residues poses a potential threat to environmental and human health. Graphene-based materials are highly stable, recyclable and effective adsorbents for efficiently removing antibiotics from polluted water.
Chironjit Kumar Shaha +2 more
doaj +1 more source
Polymers Interfacing with Biology
The development of various controlled radical polymerization techniques as well as site- and residue specific strategies to modify peptides/proteins with synthetic polymers have made polymer chemistry a powerful tool to address materials ...
Frederik Wurm, Harm-Anton Klok
doaj +1 more source
Effect of charged lipids on the ionization behavior of glutamic acid containing transmembrane helices [PDF]
Transmembrane proteins make up critical components of living cells. Protein function can be greatly impacted by the charged state of its respective components, the side chains of amino acid residues.
Nunn, Brooke
core +2 more sources

