Results 71 to 80 of about 2,876,597 (260)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A Redundant Residue Number System Coded Burst-by-Burst Adaptive Joint-Detection Based CDMA Speech Transceiver [PDF]

open access: yes, 2006
A burst-by-burst (BbB) adaptive speech transceiver is proposed, which can drop its source coding rate and speech quality under transceiver control in order to invoke a more error resilient modem mode among less favorable channel conditions.
H.T. How   +9 more
core   +2 more sources

Thermal processing of Khoot coal and characterization of obtained solid and liquid products

open access: yesMongolian Journal of Chemistry, 2014
On 21st January 2015, the abstract of this paper was replaced with the correct abstract.The coal of Khoot deposit have been investigated and determined the technical characteristics, elemental and petrographical maceral compositions.
S Batbileg   +3 more
doaj   +1 more source

Synthesis, structure and pyrolysis of stabilised phosphonium ylides containing saturated oxygen heterocycles [PDF]

open access: yes, 2016
A range of twelve stabilised phosphonium ylides containing tetrahydrofuran, tetrahydropyran or 2,2-dimethyl-1,3-dioxolane rings have been prepared and fully characterised, including one X-ray structure determination of each type.
Sahabo, Nina Carole   +10 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Facile Synthesis of the Naturally Cytotoxic Triterpenoid Saponin Patrinia-Glycoside B-II and Its Conformer

open access: yesMolecules, 2013
The first chemical synthesis of the natural triterpenoid saponin Patrinia-glycoside B-II, namely oleanolic acid 3-O-α-L-rhamnopyranosyl-(1→2)-[β-D-gluco-pyranosyl-(1→3)]-α-L-arabinopyranoside, has been accomplished in a linear 11-step sequence 11 with 9.
Li Ren   +6 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Efficient adsorptive removal of levofloxacin using sulfonated graphene oxide: Adsorption behavior, kinetics, and thermodynamics

open access: yesHeliyon
Water pollution by antibiotic residues poses a potential threat to environmental and human health. Graphene-based materials are highly stable, recyclable and effective adsorbents for efficiently removing antibiotics from polluted water.
Chironjit Kumar Shaha   +2 more
doaj   +1 more source

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