Results 61 to 70 of about 663,482 (304)

Noncanonical Amino Acids in the Interrogation of Cellular Protein Synthesis [PDF]

, 2011
Proteins in living cells can be made receptive to bioorthogonal chemistries through metabolic labeling with appropriately designed noncanonical amino acids (ncAAs).
Ngo, John T., Tirrell, David A.
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Thermal processing of Khoot coal and characterization of obtained solid and liquid products

Mongolian Journal of Chemistry, 2014
On 21st January 2015, the abstract of this paper was replaced with the correct abstract.The coal of Khoot deposit have been investigated and determined the technical characteristics, elemental and petrographical maceral compositions.
S Batbileg, B Purevsuren, Ya Davaajav, J Namkhainorov   +3 more
doaj   +1 more source

Phase Chemistry of Tank Sludge Residual Components [PDF]

, 2000
About four or five distinct reprocessing technologies were used at various times in Hanford's history. After removing U and Pu (or later 137Cs and 90Sr), the strongly acidic HLW was ''neutralized'' to high pH (>13) and stored in steel-lined tanks. High pH was necessary to prevent tank corrosion. While each technology produced chemically distinct waste,
Krumhansl, James L., Nagy, Kathryn L.
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Studies on the Preparation of Protomycinolide IV: Enantioselective Synthesis of the C3–C9 Segment [PDF]

, 1998
The C3–C9 segment, (−)-16, of the polyene macrolide antibiotic protomycinolide IV (1a) was prepared in optically pure form from commercially available methyl (S)-2-methyl-3-hydroxypropionate in 12 steps giving 17 ...
Donaldson, William, Wasicak, James Thomas   +1 more
core   +1 more source

Langerin-Heparin Interaction: Two Binding Sites for Small and Large Ligands as revealed by a combination of NMR Spectroscopy and Cross-Linking Mapping Experiments [PDF]

, 2015
Langerin is a C-type lectin present on Langerhans cells that mediates capture of pathogens in a carbohydrate-dependent manner, leading to subsequent internalization and elimination in the cellular organelles called Birbeck granules.
Angulo, Jesus, Chabrol, Eric, de Paz, José L, Fieschi, Franck, Imberty, Anne, Muñoz-García, Juan C., Nieto, Pedro M., Rojo, Javier, Thomas, Aline, Vives, Romain R.   +9 more
core   +7 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Facile Synthesis of the Naturally Cytotoxic Triterpenoid Saponin Patrinia-Glycoside B-II and Its Conformer

Molecules, 2013
The first chemical synthesis of the natural triterpenoid saponin Patrinia-glycoside B-II, namely oleanolic acid 3-O-α-L-rhamnopyranosyl-(1→2)-[β-D-gluco-pyranosyl-(1→3)]-α-L-arabinopyranoside, has been accomplished in a linear 11-step sequence 11 with 9.
Li Ren, Yong-Xiang Liu, Dan Lv, Mao-Cai Yan, Han Nie, Yang Liu, Mao-Sheng Cheng   +6 more
doaj   +1 more source

Reactivity of (1-methoxycarbonylpentadienyl)iron(1+) cations with hydride, methyl, and nitrogen nucleophiles [PDF]

, 2017
The reaction of tricarbonyl and (dicarbonyl)triphenylphosphine (1-methoxycarbonyl-pentadientyl)iron(1+) cations 7 and 8 with methyl lithium, NaBH3CN, or potassium phthalimide affords (pentenediyl)iron complexes 9a-c and 11a-b, while reaction with ...
Anobick Sar, Brown, Casas-Solvas, Cox, Creary, Donaldson, Donaldson, Donaldson, Donaldson, Donaldson, Donaldson, El Amouri, Ferber, Gree, Gree, Hanessian, Hossain, Iwata, Jaouen, Jayapal Reddy Gone, Julie Wondergem (nee Lukesh), Kausch-Busies, Knoelker, Kocsis, Konno, Laabassi, Lee, Lehmann, Lehmann, Li, Lukesh, Luyt, Morey, Motiei, Osella, Pandey, Pearson, Pinsard, Rostovtsev, Sergey Lindeman, Siddiquee, Sorenson, Sudhir, Sudhir, Szanti-Pinter, Szanti-Pinter, Szanti-Pinter, Tao, Top, Top, Trakossas, Wallock, Wasicak, William A. Donaldson, Ye, Young K. Yun, Yun, Yun, Yuzhi Ma   +58 more
core   +2 more sources