Unraveling Mutation-Induced Protein Communication Pathways in the Actomyosin Complex: Insights from Comprehensive Metadynamics Simulations. [PDF]
Ghanta KP, Tardiff JC, Schwartz SD.
europepmc +1 more source
Die Triflylgruppe, ein hervorragend geeigneter Rest für SN2-Austausch in der Kohlenhydratchemie / The Triflate Group, an Excellent Suitable Residue for SN2 Exchange in Carbohydrate Chemistry [PDF]
Reinhard Kimmich+3 more
openalex +1 more source
Elucidation of the Molecular Interaction Network Underlying Full-Length FUS Conformational Transitions and Its Phase Separation Using Atomistic Simulations. [PDF]
Weng SL, Mohanty P, Mittal J.
europepmc +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Resource Utilization of the Electrolytic Manganese Residue in Unfired Bricks: Pretreatment, Strength Enhancement, and Microwave Absorption Properties. [PDF]
Chen N+6 more
europepmc +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Mutation of an Active Site Residue of Tryptophan Synthase (β-Serine 377) Alters Cofactor Chemistry [PDF]
Kwang-Hwan Jhee+5 more
openalex +1 more source