Results 251 to 260 of about 1,955,453 (343)

Lipopeptide ligands captured by MHC class I molecules undergo dynamic conformational changes that affect their antigenic strength. [PDF]

J Biol Chem
Morita D, Fujii T, Inuki S, Suzuki H, Mikami B, Sugita M.   +5 more
europepmc   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Residue-Based Thermogravimetric Analysis: A Novel Method to Quantify Carboxylate Group Modifications in Macromolecules. [PDF]

Biomacromolecules
Leliopoulos C, Mokhtari H, Tavakoli S, Varghese OP.   +3 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Chemical Synthesis of Human Milk Oligosaccharides: Sialyllacto-<i>N</i>-Tetraose a (LSTa). [PDF]

J Org Chem
Das A, De Meo C, Demchenko AV.
europepmc   +1 more source

Profiling the proteome-wide selectivity of diverse electrophiles. [PDF]

Nat Chem
Zanon PRA, Yu F, Musacchio PZ, Lewald L, Zollo M, Krauskopf K, Mrdović D, Raunft P, Maher TE, Cigler M, Chang CJ, Lang K, Toste FD, Nesvizhskii AI, Hacker SM.   +14 more
europepmc   +1 more source

The disposal of chemical residues and the relationships between science, technology and society (cts) in chemistry teaching

, 2018
Magaly Martins Brandão, http://lattes.cnpq.br/1607594561662219   +1 more
openalex   +1 more source

Large-Scale Amino-Hydroxylation Using Tethered Nitreniums. [PDF]

Organic Synth
Sathyamoorthi S.
europepmc   +1 more source

Crystal structure of a short-chain dehydrogenase from Brucella ovis with apo and coenzyme NAD⁺-bound protomer chains. [PDF]

Acta Crystallogr F Struct Biol Commun
Zupko SP, Konstanty AT, Mayclin SJ, Choi R, Serbzhinskiy D, Robles E, Moses V, Barrett LK, Van Voorhis WC, Edwards TE, Myler PJ, Torelli AT, French JB, Hicks KA.   +13 more
europepmc   +1 more source

Green Extraction of Bioactive Compounds from Plant-Based Agri-Food Residues: Advances Toward Sustainable Valorization. [PDF]

Plants (Basel)
Kagueyam SS, Dos Santos Filho JR, Contato AG, de Souza CGM, Castoldi R, Corrêa RCG, Conte Junior CA, Yamaguchi NU, Bracht A, Peralta RM.   +9 more
europepmc   +1 more source